Evidence map›Paper›PMID 35933442›Full record

ReviewParticle and fibre toxicology2022

Coronas of micro/nano plastics: a key determinant in their risk assessments.

Jiayu Cao, Qing Yang, Jie Jiang, Tatenda Dalu, Aliaksei Kadushkin, Joginder Singh, Rawil Fakhrullin, Fangjun Wang, Xiaoming Cai, Ruibin Li

Open access · goldAbstract readReview
In one paragraph

Review in Particle and fibre toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 143 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
  6. Article
  7. The Opposite Roles of Benzo[Environment & health (Washington, D.C.) · 2026
    Article
  8. Article
  9. Caenorhabditis elegans as an Alternative Model in Pharmacological and Toxicological Studies Involving Microplastics.Water environment research : a research publication of the Water Environment Federation · 2026
    Article
  10. Review
  11. Microplastics, nanoplastics and liver disease: an emerging health concern?Nature reviews. Gastroenterology & hepatology · 2026
    Review
  12. Plastic particle risk is shaped by transformation history.Environmental science and ecotechnology · 2026
    Article
  13. Article
  14. Review
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Jiayu CaoSchool of Public Health, Soochow University, Suzhou, 215123, Jiangsu, China.
Qing YangSchool of Public Health, Soochow University, Suzhou, 215123, Jiangsu, China.
Jie JiangState Key Laboratory of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, Jiangsu, China.
Tatenda DaluSchool of Biology and Environmental Sciences, University of Mpumalanga, Nelspruit, 1200, South Africa.
Aliaksei KadushkinDepartment of Biological Chemistry, Belarusian State Medical University, 220116, Minsk, Belarus.
Joginder SinghDepartment of Microbiology, Lovely Professional University, Phagwara, Punjab, 144411, India.
Rawil FakhrullinKazan Federal University, Institute of Fundamental Medicine & Biology, Kreml Uramı 18, Kazan, Republic of Tatarstan, Russian Federation, 420008.
Fangjun WangDalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian, 116023, Liaoning, China.
Xiaoming CaiSchool of Public Health, Soochow University, Suzhou, 215123, Jiangsu, China. xmcai@suda.edu.cn.
Ruibin LiState Key Laboratory of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, Jiangsu, China. liruibin@suda.edu.cn.
Soochow University · CNBelarusian State Medical University · BYChinese Academy of Sciences · CNKazan Federal University · RULovely Professional University · INUniversity of Mpumalanga · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an emerging pollutant in the life cycle of plastic products, micro/nanoplastics (M/NPs) are increasingly being released into the natural environment. Substantial concerns have been raised regarding the environmental and health impacts of M/NPs. Although diverse M/NPs have been detected in natural environment, most of them display two similar features, i.e.,high surface area and strong binding affinity, which enable extensive interactions between M/NPs and surrounding substances. This results in the formation of coronas, including eco-coronas and bio-coronas, on the plastic surface in different media. In real exposure scenarios, corona formation on M/NPs is inevitable and often displays variable and complex structures. The surface coronas have been found to impact the transportation, uptake, distribution, biotransformation and toxicity of particulates. Different from conventional toxins, packages on M/NPs rather than bare particles are more dangerous. We, therefore, recommend seriously consideration of the role of surface coronas in safety assessments. This review summarizes recent progress on the eco-coronas and bio-coronas of M/NPs, and further discusses the analytical methods to interpret corona structures, highlights the impacts of the corona on toxicity and provides future perspectives.

Indexed as

Environmental PollutantsNanoparticlesMicroplasticsRisk AssessmentEnvironmental PollutantsMicroplasticsBiotransformationCoronaMicro/nanoplasticsNanotoxicityStructure–activity relationship

Identifiers

PMID35933442
PMCPMC9356472
OpenAlexW4290026722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.