Evidence map›Paper›PMID 35933357›Full record

ArticleBMC surgery2022

Hemophilia A developing cerebral infarction after surgical treatment of giant hemophilic pseudotumor: a case report.

Yiqing Ling, Zhenyu Shi, Chenying Su, Xiaochen Liu, Lingxin Zheng, Xiaohao Pan, Yan Sun, Xuan Zhang, Jinling Wei, Ju Li and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yiqing Ling *The First Affiliated Hospital of Zhejiang, Chinese Medical University, You Dian Road No.54, Hangzhou, 310006, Zhejiang Province, People's Republic of China.
Zhenyu Shi *The First Affiliated Hospital of Zhejiang, Chinese Medical University, You Dian Road No.54, Hangzhou, 310006, Zhejiang Province, People's Republic of China.
Chenying SuThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, People's Republic of China.
Xiaochen LiuUniversity of Toledo Medical Center, Toledo, OH, 43614, USA.
Lingxin ZhengZhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, People's Republic of China.
Xiaohao PanZhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, People's Republic of China.
Yan SunZhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, People's Republic of China.
Xuan ZhangZhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, People's Republic of China.
Jinling WeiTongde Hospital of Zhejiang Province, Hangzhou, 310007, Zhejiang, People's Republic of China.
Ju LiThe First Affiliated Hospital of Zhejiang, Chinese Medical University, You Dian Road No.54, Hangzhou, 310006, Zhejiang Province, People's Republic of China.
Peijian TongThe First Affiliated Hospital of Zhejiang, Chinese Medical University, You Dian Road No.54, Hangzhou, 310006, Zhejiang Province, People's Republic of China.
Taotao XuThe First Affiliated Hospital of Zhejiang, Chinese Medical University, You Dian Road No.54, Hangzhou, 310006, Zhejiang Province, People's Republic of China. xut@zcmu.edu.cn.ORCID http://orcid.org/0000-0002-2697-1484
Zhejiang Chinese Medical University · CNTongde Hospital of Zhejiang Province · CNUniversity of Toledo Medical Center · USWenzhou Medical University · CN

Funding

Bethune Charitable Foundation G-X-2020-1107-17Medical Health Science and Technology Program of Zhejiang Province 2020KY659National Natural Science Foundation of China 81904223Talent Cultivation Project of Zhejiang Association for Science and Technology CTZB-2020080127Youth Research and Innovation Fund of Zhejiang Chinese Medical University KC201933
6 · The paper itself

Abstract

backgroundCerebral infarction (CI) is an unusual complication in patients with bleeding disorders. To our knowledge, this is the first case of postoperative internal border-zone infarction (I-BZI) from Hemophilia A. CASE PRESENTATION: We present a case of Hemophilia A developing I-BZI, after surgical treatment of giant hemophilic pseudotumor. A 36-year-old man was introduced from other hospital by Hemophilia with giant hemophilic pseudotumor in his left thigh. Patient and his relatives did not have a history of thrombophilia. After excluding the relevant surgical contraindications, we performed the operation of pseudotumor resection. Prior to surgery, blood tests revealed hemoglobin of 137 g/L. FVIII activity was 1.5%. Activated partial thromboplastin time (APTT) was 71.50 s and D-dimer was 3.33 mg/L FEU. Immediately before surgery, the patient received an intravenous infusion of FVIII products (Xyntha

conclusionsFor the treatment of I-BZI caused by acute anemia from Hemophilia A, volume expansion, red blood cell supplement and continuous improvement of coagulation with suitable dose of factor VIII (FVIII) should be considered to improve prognosis.

Indexed as

Hemophilia AAdultCerebral InfarctionHumansMagnetic Resonance ImagingMaleThighCase reportCerebral infarctionFactor VIII deficiencyHemophilia AHemophilic pseudotumor

Identifiers

PMID35933357
PMCPMC9357307
OpenAlexW4290068965

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.