Evidence map›Paper›PMID 35933331›Full record

ArticleBMC ophthalmology2022

Corneal endothelial cell density and its correlation with birth weight, anthropometric parameters, and ocular biometric parameters in Chinese school children.

Zijin Wang, Xiaoxia Zuo, Lei Liu, Xuejuan Chen, Rui Li, Hui Zhu, Dan Huang, Haohai Tong, Xiaoyan Zhao, Wen Yan and 8 more

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Repeatability and reproducibility of corneal endothelial measurements using the topcon SP-1P specular microscope.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Zijin Wang *Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Xiaoxia Zuo *Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Lei Liu *Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Xuejuan ChenDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Rui LiDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Hui ZhuDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Dan HuangDepartment of Child Healthcare, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China.
Haohai TongEye Center, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiaoyan ZhaoDepartment of Ophthalmology, the Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.
Wen YanDepartment of Ophthalmology, The Fourth Affiliated Hospital of Nantong University, Yancheng, China.
Shiya ShenDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Yun WangDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Xiaoxiao LiDepartment of Ophthalmology, Children's Hospital of Soochow University, Suzhou, China.
Andi ZhaoDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Danni ChenDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Ranran DingThe Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Shiding LiThe Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Hu LiuDepartment of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China. liuhu@njmu.edu.cn.
Nanjing Medical University · CNSecond Affiliated Hospital of Nanjing Medical University · CNChangzhou No.2 People's Hospital · CNNantong University · CNSecond Affiliated Hospital of Zhejiang University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe the distribution of corneal endothelial cell density (ECD), and to explore its correlation with birth weight (BW), anthropometric parameters, and ocular biometric parameters in Chinese school children.

methodsIn the population-based cross-sectional Nanjing Eye Study, children were measured for anthropometric information, for ECD by the noncontact specular microscope and for ocular biometric parameters by the optic low-coherent reflectometer. Data from right eyes were analyzed to illustrate the distribution of ECD and for determining correlated factors with ECD using univariate and multiple linear regression analysis. Comparisons among three different BW groups were performed using a one-way ANOVA analysis followed by the Bonferroni correction for pairwise comparisons.

resultsOf 1171 children, the mean (± standard deviation) ECD was 2875.34 ± 195.00 cells/mm

conclusionsIn Chinese school children aged 82 to 94 months, the ECD is positively correlated with BW and central corneal thickness, in which BW is a newly identified associated factor. It is like that gender plays an important role in ECD distribution while girls have relatively greater ECD than boys.

Indexed as

BiometryEndothelium, CornealBirth WeightCell CountChildChinaCross-Sectional StudiesEndothelial CellsFemaleHumansMaleBirth weightBody mass indexCorneal endothelial cell densityEpidemiologyOcular parameters

Identifiers

PMID35933331
PMCPMC9356483
OpenAlexW4289977647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.