Evidence map›Paper›PMID 35933328›Full record

Trial reportBMC anesthesiology2022

The Pericapsular Nerve Group (PENG) block combined with Local Infiltration Analgesia (LIA) compared to placebo and LIA in hip arthroplasty surgery: a multi-center double-blinded randomized-controlled trial.

D-Yin Lin, Brigid Brown, Craig Morrison, Nikolai S Fraser, Cheryl S L Chooi, Matthew G Cehic, David H McLeod, Michael D Henningsen, Nikolina Sladojevic, Hidde M Kroon and 1 more

5 registry-linked trialsOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05773365 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Evaluation of Analgesic Effect of Added Local Infiltration to Pericapsular Nerve Group Block in Traumatic Hip Surgery

TypeinterventionalSponsorSuez Canal UniversityRan2023 to 2025Enrolled122ConditionsPain, Hip Fractures, Postoperative Pain, Postoperative AnalgesiaArmsPENG block with or without local anaesthetic infiltration
NCT05898581 narecruitingnot on this mapstarted 2024, after this paper: background citation

Ultrasound-guided Pericapsular Nerve Group (PENG) Block vs. Intraoperative Local Anesthetic Infiltration (ILAI) for Total Hip Arthroplasty (THA): a Single Center, Non-inferiority Randomized Control Trial Pilot Study.

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2024 to 2026Enrolled60ConditionsAnesthesiaArmsPENG Block, Control Group
NCT05941221 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Pericapsular Nerve Group (PENG) Block for Perioperative Analgesia in Geriatric Patients With Hip Fractures

TypeinterventionalSponsorAin Shams UniversityRan2023 to 2023Enrolled16ConditionsHip FracturesArmspericapsular nerve group (PENG) block
NCT06166602 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparison of the Impacts of Ultrasound-guided Pericapsular Nerve Group (PENG) Block Applied in Different Volumes on Postoperative Pain in Hip Replacement Surgeries: A Randomized Clinical Trial

TypeinterventionalSponsorIstanbul Medeniyet UniversityRan2023 to 2023Enrolled50ConditionsRegional Anesthesia, Postoperative Pain, Hip SurgeryArmsPENG block with 0.25% bupivacaine.
NCT06317870 narecruitingnot on this mapstarted 2024, after this paper: background citation

Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty: a Double Blind, Non-inferiority Study

TypeinterventionalSponsorCentre Hospitalier Universitaire VaudoisRan2024 to 2027Enrolled80ConditionsAnalgesia, Hip Arthropathy, Post Operative PainArmsIntrathecal morphine, Pericapsular nerve group block (PENG)
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pericapsular nerve group block for total hip arthroplasty: A systematic review.The Journal of international medical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

D-Yin Lin *Department of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia. d-yin.lin@sa.gov.au.
Brigid Brown *Department of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia.
Craig MorrisonDepartment of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia.
Nikolai S FraserDepartment of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia.
Cheryl S L ChooiDepartment of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia.
Matthew G CehicDepartment of Orthopaedic and Trauma Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia.
David H McLeodDepartment of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia.
Michael D HenningsenDepartment of Orthopaedic and Trauma Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia.
Nikolina SladojevicDepartment of Anesthesiology, Flinders Medical Centre, Flinders Drive, Bedford Park, Adelaide, South Australia, 5042, Australia.
Hidde M KroonDepartment of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Ruurd L JaarsmaDepartment of Orthopaedic and Trauma Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia.
Flinders Medical Centre · AUFlinders University · AURoyal Adelaide Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe PEricapsular Nerve Group (PENG) block is a novel regional analgesia technique that provides improved analgesia in patients undergoing hip surgery while preserving motor function. In this study the PENG block was investigated for analgesia in elective total hip arthroplasty (THA).

methodsIn this multi-centre double-blinded randomized-controlled trial, in addition to spinal anesthesia and local infiltration analgesia (LIA), THA patients received either a PENG block or a sham block. The primary outcome was pain score (numeric rating scale 0-10) 3 h postoperatively (Day 0). Secondary outcomes were postoperative quadriceps muscle strength, postoperative Day 1 pain scores, opiate use, complications, length of hospital stay, and patient-reported outcome measures.

resultsSixty patients were randomized and equally allocated between groups. Baseline demographics were similar. Postoperative Day 0, the PENG group experienced less pain compared to the sham group (PENG: 14 (47%) patients no pain, 14 (47%) mild pain, 2 (6%) moderate/severe pain versus sham: 6 (20%) no pain, 14 (47%) mild pain, 10 (33%) moderate/severe pain; p = 0.03). There was no difference in quadriceps muscle strength between groups on Day 0 (PENG: 23 (77%) intact versus sham: 24 (80%) intact; p = 0.24) and there were no differences in other secondary outcomes.

conclusionsPatients receiving a PENG block for analgesia in elective THA experience less postoperative pain on Day 0 with preservation of quadriceps muscle strength. Despite these short-term benefits, no quality of recovery or longer lasting postoperative effects were detected.

Indexed as

AnalgesiaArthroplasty, Replacement, HipArthroplasty, Replacement, KneeNerve BlockAnesthetics, LocalFemoral NerveHumansPostoperative PainAnesthetics, LocalAnalgesiaAnesthesiaHip arthroplastyPainPatient reported outcome measuresPENGPericapsular nerve group blockPROMsRegional analgesiaSham

Identifiers

PMID35933328
PMCPMC9356515
OpenAlexW4289981935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.