Evidence map›Paper›PMID 35933230›Full record

ArticleTransplantation proceedings2022

Pretransplant Psoas Muscle Cross-Sectional Area and Postkidney Transplant Outcomes.

Taylor Norris, Robert Montgomery, Diane Cibrik, Mark Reintjes, Shweta Chakraborty, Shelby Fishback, Aditi Gupta

Open access · greenAbstract read
In one paragraph

Article in Transplantation proceedings, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Taylor NorrisDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Robert MontgomeryDepartment of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, Kansas.
Diane CibrikDivision of Nephrology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Mark ReintjesDepartment of Surgery, University of Kansas Medical Center, Kansas City, Kansas.
Shweta ChakrabortyDepartment of Radiology, University of Kansas Medical Center, Kansas City, Kansas.
Shelby FishbackDepartment of Radiology, University of Kansas Medical Center, Kansas City, Kansas.
Aditi GuptaDivision of Nephrology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas. Electronic address: agupta@kumc.edu.
University of Kansas Medical Center · US

Funding

Cognitive Impairment in End Stage Renal DiseaseK23AG055666 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI GUPTA, ADITI · 2017 to 2022
$1.2M
NIA NIH HHS K23 AG055666
6 · The paper itself

Abstract

backgroundSarcopenia is associated with adverse outcomes in end-stage kidney disease. We evaluated if pretransplant sarcopenia affects posttransplant outcomes in kidney transplant (KT) recipients.

methodsIn this single-center retrospective study of adult patients with end-stage kidney disease, we analyzed the association between pre-KT psoas muscle cross-sectional area and critical posttransplant outcomes of decline in estimated glomerular filtration rate (eGFR), graft loss, rehospitalization, and mortality using Cox proportional hazard model adjusted for age, sex, and race.

resultsPre-KT abdomen and pelvic computed tomography scans performed during evaluation for KT eligibility were available for 573 KT recipients. Of these, 465 KT recipients received kidney alone transplant, 71 received simultaneous liver kidney transplant (SLK), and 37 received simultaneous pancreas kidney transplant (SPK). Patients were 49 (SD, 13) years old, 16% Black, and 60% men. For kidney alone transplant recipients, a higher psoas muscle cross-sectional area was associated with a shorter length of hospitalization (β coefficient = -0.003; 95% CI, -0.005 to -0.0007). Conversely, pre-KT psoas muscle cross-sectional area did not predict decline in eGFR, graft loss, mortality, or early rehospitalization. For SLK recipients, psoas muscle cross-sectional area did not predict any of the priori outcomes. For SPK recipients, higher pretransplant psoas muscle cross-sectional area predicted a longer length of hospitalization (β coefficient = 0.03; 95% CI, 0.01-0.05). There was no association between psoas muscle cross-sectional area and other outcomes assessed.

conclusionsPretransplant psoas muscle cross-sectional areas are not predictive of post-transplant decline in eGFR, graft loss, rehospitalization or mortality in kidney alone, SPK, or SLK transplants.

Indexed as

Kidney Failure, ChronicSarcopeniaAdolescentAdultFemaleGraft SurvivalHumansMalePsoas MusclesRetrospective StudiesRisk Factors

Identifiers

PMID35933230
PMCPMC10506176
OpenAlexW4289838075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.