Evidence map›Paper›PMID 35932912›Full record

ArticleAmerican heart journal2022

Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.

Stephen Y Wang, Jonathan M Hanna, Prajesh Gongal, Oyere K Onuma, Michael G Nanna

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American heart journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephen Y WangDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT.
Jonathan M HannaDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT.
Prajesh GongalDepartment of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH.
Oyere K OnumaSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.
Michael G NannaSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT. Electronic address: michael.nanna@yale.edu.
Yale University · USDartmouth–Hitchcock Medical Center · US

Funding

Generating novel predictive models to estimate the risk of future ASCVD & Dementia in older adultsR03AG074067 · NIA · YALE UNIVERSITY · PI NANNA, MICHAEL · 2021 to 2022
$335k
NIA NIH HHS R03 AG074067
6 · The paper itself

Abstract

Despite broad treatment recommendations, there are limited published reports comparing the efficacy of different antihypertensive agents in patients with isolated systolic hypertension or isolated diastolic hypertension. This study was a secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. We compared the use of chlorthalidone, amlodipine, or lisinopril on the primary outcome of combined coronary heart disease, stroke, or all-cause mortality in patients with isolated systolic hypertension or isolated diastolic hypertension.

Indexed as

HypertensionIsolated Systolic HypertensionAmlodipineAntihypertensive AgentsChlorthalidoneHumansLisinoprilTreatment OutcomeAmlodipineAntihypertensive AgentsChlorthalidoneLisinopril

Identifiers

PMID35932912
PMCPMC10908340
OpenAlexW4289732055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.