Evidence map›Paper›PMID 35932761›Full record

ArticleCurrent biology : CB2022

Broad-spectrum chemicals block ROS detoxification to prevent plant fungal invasion.

Qianqian Yang, Jinguang Yang, Yameng Wang, Juan Du, Jianan Zhang, Ben F Luisi, Wenxing Liang

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 47 citations in OpenAlex.

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  12. Challenges and Opportunities Arising from Host-International journal of molecular sciences · 2024
    Review
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  14. Early and Late Transcriptomic and Metabolomic Responses ofInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
  17. Biocontrol potential of lipopeptides produced byFrontiers in microbiology · 2023
    Article
  18. Plants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Qianqian YangCollege of Plant Health and Medicine, Engineering Research Center for Precision Pest Management for Fruits and Vegetables of Qingdao, Shandong Engineering Research Center for Environment-Friendly Agricultural Pest Management, Shandong Province Key Laboratory of Applied Mycology, Qingdao Agricultural University, Qingdao 266109, China.
Jinguang YangTobacco Research Institute of CAAS, Qingdao 266100, China.
Yameng WangCollege of Plant Health and Medicine, Engineering Research Center for Precision Pest Management for Fruits and Vegetables of Qingdao, Shandong Engineering Research Center for Environment-Friendly Agricultural Pest Management, Shandong Province Key Laboratory of Applied Mycology, Qingdao Agricultural University, Qingdao 266109, China.
Juan DuCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Jianan ZhangCollege of Plant Health and Medicine, Engineering Research Center for Precision Pest Management for Fruits and Vegetables of Qingdao, Shandong Engineering Research Center for Environment-Friendly Agricultural Pest Management, Shandong Province Key Laboratory of Applied Mycology, Qingdao Agricultural University, Qingdao 266109, China.
Ben F LuisiDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.
Wenxing LiangCollege of Plant Health and Medicine, Engineering Research Center for Precision Pest Management for Fruits and Vegetables of Qingdao, Shandong Engineering Research Center for Environment-Friendly Agricultural Pest Management, Shandong Province Key Laboratory of Applied Mycology, Qingdao Agricultural University, Qingdao 266109, China. Electronic address: wliang1@qau.edu.cn.
Qingdao Agricultural University · CNTobacco Research Institute · CNUniversity of Cambridge · GB

Funding

Wellcome Trust 200873Wellcome Trust 222451/Z/21/Z
6 · The paper itself

Abstract

Plant diseases cause a huge impact on food security and are of global concern. While application of agrochemicals is a common approach in the control of plant diseases currently, growing drug resistance and the impact of off-target effects of these compounds pose major challenges. The identification of pathogenicity-related virulence mechanisms and development of new chemicals that target these processes are urgently needed. One such virulence mechanism is the detoxification of reactive oxygen species (ROS) generated by host plants upon attack by pathogens. The machinery of ROS detoxification might therefore serve as a drug target for preventing plant diseases, but few anti-ROS-scavenging drugs have been developed. Here, we show that in the model system Botrytis cinerea secretion of the cytochrome c-peroxidase, BcCcp1 removes plant-produced H

Indexed as

Fungicides, IndustrialBotrytisCytochromes cFungal ProteinsHydrogen PeroxidePeroxidasesPlant DiseasesReactive Oxygen SpeciesCytochromes cFungal ProteinsFungicides, IndustrialHydrogen PeroxidePeroxidasesReactive Oxygen SpeciesBcTol1Botrytis cinereacytochrome c-peroxidaselysine acetylationROSvirulence

Identifiers

PMID35932761
PMCPMC7613639
OpenAlexW4289937685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.