Evidence map›Paper›PMID 35932644›Full record

ArticleThe International journal on drug policy2022

Peer recovery specialist-delivered, behavioral activation intervention to improve retention in methadone treatment: Results from an open-label, Type 1 hybrid effectiveness-implementation pilot trial.

Jessica F Magidson, Mary B Kleinman, Valerie Bradley, Morgan S Anvari, Tolulope M Abidogun, Annabelle M Belcher, Aaron D Greenblatt, Dwayne Dean, Abigail Hines, C J Seitz-Brown and 3 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal on drug policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05973838 (Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural Area), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05973838 narecruitingnot on this mapstarted 2023, after this paper: background citation

Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural Area

TypeinterventionalSponsorUniversity of Maryland, College ParkRan2023 to 2027Enrolled160ConditionsPolysubstance Addiction, Opioid Medication Assisted Treatment, Treatment Adherence, Retention in CareArmsPeer-Delivered Behavioral Activation ("Peer Activate")
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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  5. The Drug Market's Impact on the Overdose Risk Environment for Women Who Use Drugs During the COVID-19 Pandemic.Journal of urban health : bulletin of the New York Academy of Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jessica F MagidsonDepartment of Psychology, University of Maryland, College Park, MD, USA. Electronic address: jmagidso@umd.edu.
Mary B KleinmanDepartment of Psychology, University of Maryland, College Park, MD, USA.
Valerie BradleyDepartment of Psychology, University of Maryland, College Park, MD, USA.
Morgan S AnvariDepartment of Psychology, University of Maryland, College Park, MD, USA.
Tolulope M AbidogunDepartment of Psychology, University of Maryland, College Park, MD, USA.
Annabelle M BelcherDepartment of Psychiatry, University of Maryland, Baltimore, MD, USA.
Aaron D GreenblattDepartment of Psychiatry, University of Maryland, Baltimore, MD, USA.
Dwayne DeanDepartment of Psychology, University of Maryland, College Park, MD, USA.
Abigail HinesDepartment of Psychology, University of Maryland, College Park, MD, USA.
C J Seitz-BrownDepartment of Psychology, University of Maryland, College Park, MD, USA.
Michael WagnerDepartment of Psychology, University of Maryland, College Park, MD, USA.
Melanie BennettDepartment of Psychiatry, University of Maryland, Baltimore, MD, USA.
Julia W FeltonCenter for Health Policy & Health Services Research, Henry Ford Health System, Detroit, MI, USA.
University of Maryland, College Park · USUniversity of Maryland, Baltimore · USHenry Ford Health System · US

Funding

The influence of neighborhood factors and social determinants of health on OUD treatment outcomesR33DA057747 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F · 2022 to 2024
$2.6M
Understanding the Impact of COVID-19 on Methadone Treatment Retention and Adherence in an Underserved, Minority Population with OUDR61AT010799 · NCCIH · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F · 2019 to 2020
$1.2M
NCCIH NIH HHS R61 AT010799NIDA NIH HHS R33 DA057747
6 · The paper itself

Abstract

backgroundDespite the efficacy of methadone to treat opioid use disorder (OUD), retention is an urgent priority, particularly among low-income, minoritized populations. Peer recovery specialists are well-positioned to engage vulnerable patients, particularly when trained in an evidence-based intervention to promote retention. This hybrid effectiveness-implementation pilot trial aimed to demonstrate the proof of concept of a peer recovery specialist-delivered behavioral activation and problem solving-based approach (Peer Activate) to improve methadone retention.

methodsImplementation outcomes included feasibility, acceptability, and fidelity. Feasibility and acceptability were defined by the percentage of participants who initiated the intervention (≥75%) and completed ≥75% of core sessions, respectively. Fidelity was assessed via independent rating of a randomly selected 20% of sessions. The primary effectiveness outcome was methadone retention at three-months post-intervention vs. a comparison cohort initiating methadone during the same time period. Secondary outcomes included methadone adherence, substance use frequency, and substance use-related problems.

resultsBenchmarks for feasibility and acceptability were surpassed: 86.5% (32/37) initiated the intervention, and 81.3% of participants who initiated attended ≥75% of core sessions. The mean independent rater fidelity score was 87.9%, indicating high peer fidelity. For effectiveness outcomes, 88.6% of participants in Peer Activate were retained in methadone treatment at three-months post-intervention-28.9% higher than individuals initiating methadone treatment alone in the same time period [χ

conclusionGiven the rapid scale-up of peer recovery specialist programs nationwide and the urgent need to promote methadone retention, these results, although preliminary, have important potential clinical significance. The next steps are to conduct a Type 1 hybrid effectiveness-implementation randomized trial with a larger sample size and longer-term follow-up to further establish the implementation and effectiveness of the Peer Activate approach.

Indexed as

MethadoneOpioid-Related DisordersBehavior TherapyHumansPilot ProjectsPovertyMethadoneBehavioral activationHealth disparitiesMethadone treatmentOpioid use disorderPeer recovery specialistTreatment retention

Identifiers

PMID35932644
PMCPMC9590100
OpenAlexW4289549747

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.