Evidence map›Paper›PMID 35932329›Full record

SynthesisEuropean journal of nuclear medicine and molecular imaging2022

The value of FDG PET/CT imaging in outcome prediction and response assessment of lymphoma patients treated with immunotherapy: a meta-analysis and systematic review.

Zahra Kiamanesh, Narjess Ayati, Ramin Sadeghi, Eliza Hawkes, Sze Ting Lee, Andrew M Scott

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Comparison of pre-treatmentEuropean radiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. British journal of haematology · 2024
    Article
  9. Article
  10. Baseline and earlyCancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  11. Article
  12. The role of baselineTherapeutic advances in medical oncology · 2024
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zahra KiamaneshNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Narjess AyatiDepartment of Nuclear Medicine, Ultrasound & PET, Sydney Westmead Hospital, Sydney, NSW, Australia.
Ramin SadeghiNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Eliza HawkesOlivia Newton-John Cancer Research Institute and School of Cancer Medicine, La Trobe University, Victoria, Australia.
Sze Ting LeeOlivia Newton-John Cancer Research Institute and School of Cancer Medicine, La Trobe University, Victoria, Australia.
Andrew M ScottOlivia Newton-John Cancer Research Institute and School of Cancer Medicine, La Trobe University, Victoria, Australia. andrew.scott@austin.org.au.ORCID 0000-0002-6656-295X
La Trobe University · AUMashhad University of Medical Sciences · IRThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTreatment strategies of lymphoid malignancies have been revolutionized by immunotherapy. Because of the inherent property of Hodgkin lymphoma and some subtypes of non-Hodgkin lymphoma as a highly FDG-avid tumor, functional

methodsA comprehensive literature search of the PubMed database was conducted on the value of the

resultsFrom the initial 1488 papers identified, 91 were ultimately included in our study. In anti-CD20 therapy, the highest pooled hazard ratios (HRs) of baseline, early, and late response monitoring parameters for progression-free survival (PFS) belong to metabolic tumor volume (MTV) (3.19 (95%CI: 2.36-4.30)), maximum standardized uptake value (SUVmax) (3.25 (95%CI: 2.08-5.08)), and Deauville score (DS) (3.73 (95%CI: 2.50-5.56)), respectively. These measurements for overall survival (OS) were MTV (4.39 (95%CI: 2.71-7.08)), DS (3.23 (95%CI: 1.87-5.58)), and DS (3.64 (95%CI: 1.40-9.43)), respectively. Early and late

conclusionFor anti-CD20 therapy of lymphoma, the MTV as a baseline

Indexed as

Fluorodeoxyglucose F18LymphomaAntigens, CD20HumansImmune Checkpoint InhibitorsImmunotherapyPositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesAntigens, CD20Fluorodeoxyglucose F18Immune Checkpoint Inhibitors18F-FDG PET/CTAnti-CD20 antibodiesImmune checkpoint inhibitorsImmunotherapyMalignant lymphoma

Identifiers

PMID35932329
PMCPMC9606078
OpenAlexW4290005545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.