Evidence map›Paper›PMID 35932321›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Legal obligation in the general population: face mask influence on endophthalmitis after intravitreal injection.

Jonas Neubauer, Konstantinos Gklavas, Friederike Kortüm, Mariya Gosheva, Karl Ulrich Bartz-Schmidt, Focke Ziemssen

Open access · hybridAbstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jonas NeubauerCenter for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany. StudyJN@outlook.com.ORCID http://orcid.org/0000-0002-4120-534X
Konstantinos GklavasCenter for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
Friederike KortümCenter for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
Mariya GoshevaCenter for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
Karl Ulrich Bartz-SchmidtCenter for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
Focke ZiemssenCenter for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
STZ eyetrial · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether compulsory face masking in public life changes the incidence or pattern of post-injection endophthalmitis (PIE). PATIENTS AND

methodsAll injections of bevacizumab, ranibizumab, aflibercept, dexamethasone or triamcinolone between 01/01/2015 and 12/31/2021 at the University Eye Clinic of Tuebingen were included in this retrospective analysis. The injection procedure itself was unchanged since 2015 and included the use of a sterile drape covering the head up to the shoulders which prevents airflow toward the eye. Furthermore, all staff wore a face mask and gloves at all times. The two study periods were defined by the introduction of a compulsory face masking rule in public life (01/01/2015 until 04/27/2020 vs. 04/28/2020 until 12/31/2021).

resultsA total of 83,543 injections were performed in the tertiary eye clinic, associated with a total of 20 PIE (0.024%, 1/4177 injections). Of these, thirteen PIE were documented during the pre-pandemic period (0.021%, 1/4773 injections) and seven PIE during the pandemic period (0.033%, 1/3071 injections). No significant difference in PIE risk was observed (p = 0.49), and there was no case of oral flora associated PIE.

conclusionAlthough some potential confounders (wearing time, skin flora) could not be considered, there was no clear signal that the introduction of compulsory face masking in public life did alter the risk for PIE in our patient population. Three and six months after PIE, no difference in visual acuity was detectable between the two study periods.

Indexed as

EndophthalmitisEye Infections, BacterialAngiogenesis InhibitorsBevacizumabHumansIncidenceIntravitreal InjectionsMasksRanibizumabRetrospective StudiesVascular Endothelial Growth Factor AAngiogenesis InhibitorsBevacizumabRanibizumabVascular Endothelial Growth Factor ABacteriaCovid-19EndophthalmitisFace maskIntravitreal injectionPost-injection endophthalmitis

Identifiers

PMID35932321
PMCPMC9362425
OpenAlexW4290005551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.