Evidence map›Paper›PMID 35931974›Full record

ArticleBMC pregnancy and childbirth2022

Hemoglobin differences in twins are related to the time of cord clamping, not intertwin transfusion - a prospective cohort study.

Katarzyna Kosińska-Kaczyńska, Jacek Witwicki, Aleksandra Saletra-Bielińska, Paweł Krajewski, Adam Krysiak, Robert Brawura-Biskupski-Samaha, Izabela Walasik, Magdalena Zgliczyńska, Ewa Malicka, Iwona Szymusik

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katarzyna Kosińska-KaczyńskaDepartment of Obstetrics, Perinatology and Neonatology, the Center of Postgraduate Medical Education, Ul. Cegłowska 80, 01-809, Warsaw, Poland. katarzyna.kosinska-kaczynska@cmkp.edu.pl.
Jacek WitwickiDepartment of Neonatology of the Center, Postgraduate Medical Education, Ul. Cegłowska 80, 01-809, Warsaw, Poland.
Aleksandra Saletra-Bielińska1St Department of Obstetrics and Gynecology, Medical University of Warsaw, pl. Starynkiewicza 1/3, 02-015, Warsaw, Poland.
Paweł Krajewski1St Department of Obstetrics and Gynecology, Medical University of Warsaw, pl. Starynkiewicza 1/3, 02-015, Warsaw, Poland.
Adam KrysiakDepartment of Neonatology of the Center, Postgraduate Medical Education, Ul. Cegłowska 80, 01-809, Warsaw, Poland.
Robert Brawura-Biskupski-Samaha2Nd Department of Obstetrics and Gynecology of, the Center of Postgraduate Medical Education, ul. Cegłowska 80, 01-809, Warsaw, Poland.
Izabela WalasikStudents' Scientific Association at the 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, pl. Starynkiewicza 1/3, 02-015, Warsaw, Poland.
Magdalena Zgliczyńska2Nd Department of Obstetrics and Gynecology of, the Center of Postgraduate Medical Education, ul. Cegłowska 80, 01-809, Warsaw, Poland.
Ewa Malicka2Nd Department of Obstetrics and Gynecology of, the Center of Postgraduate Medical Education, ul. Cegłowska 80, 01-809, Warsaw, Poland.
Iwona Szymusik1St Department of Obstetrics and Gynecology, Medical University of Warsaw, pl. Starynkiewicza 1/3, 02-015, Warsaw, Poland.
Postgraduate School of Molecular Medicine · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelayed cord clamping increases placental transfusion. In vaginal deliveries higher hemoglobin concentrations are found in the second-born twin. We hypothesized it is unrelated to intertwin transfusion but to the time of cord clamping.

methodsIt was a prospective cohort study of 202 women delivering twins > 32 weeks of gestation. Monoamniotic pregnancy, antenatal intertwin transfusions, fetal demise or major abnormalities were excluded from the study. The time of cord clamping depended on the obstetrician's decision. Hemoglobin, hematocrit, and reticulocyte count were measured at birth and during the second day of life.

resultsAt birth, hemoglobin and hematocrit levels were significantly higher in the first-born twins delivered with delayed than with early cord clamping. Higher hemoglobin and hematocrit levels were observed during the second day of life in all twins delivered with delayed cord clamping. The lowest levels were observed in twins delivered with early cord clamping. Infants delivered with delayed cord clamping were at a lower risk of respiratory disorders and NICU hospitalization.

conclusionThe observed differences in Hgb concentrations between the infants in a twin pregnancy are related to cord clamping time.

Indexed as

PlacentaUmbilical CordConstrictionFemaleHemoglobinsHumansInfant, NewbornPregnancyProspective StudiesHemoglobinsAnemiaDelayed cord clampingEarly cord clampingNeonatal outcomesPolycythemiaTwin pregnancyTwin-to-twin transfusion

Identifiers

PMID35931974
PMCPMC9354348
OpenAlexW4289884236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.