Evidence map›Paper›PMID 35931969›Full record

ReviewThe journal of physiological sciences : JPS2022

Antioxidative properties of phenolic compounds and their effect on oxidative stress induced by severe physical exercise.

Joanna Kruk, Basil Hassan Aboul-Enein, Ewa Duchnik, Mariola Marchlewicz

Open access · goldAbstract readReview
In one paragraph

Review in The journal of physiological sciences : JPS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 1 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 1 synthesis or guideline pooled it, 183 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Cardioprotective and Antioxidant Effects of Marine-DerivedPharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Valorization of Tomato (Plants (Basel, Switzerland) · 2026
    Article
  11. Article
  12. Article
  13. Bioactive Metabolites fromCurrent developments in nutrition · 2026
    Article
  14. Article
  15. Review
  16. Ameliorative effects of desert truffleFrontiers in cellular and infection microbiology · 2026
    Article
  17. Review
  18. Article
  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Joanna KrukFaculty of Physical Culture and Health, University of Szczecin, Al. Piastów 40b/6, 71-065, Szczecin, Poland. joanna.kruk@usz.edu.pl.ORCID http://orcid.org/0000-0002-7551-1927
Basil Hassan Aboul-EneinDepartment of Health Science, Johnson & Wales University, College of Health & Wellness, 8 Abbott Park Place, Providence, RI, 02903, USA.
Ewa DuchnikDepartment of Aesthetic Dermatology, Pomeranian Medical University, Al. Powstańców Wielkopolskich 72, 70-111, Szczecin, Poland.
Mariola MarchlewiczDepartment of Dermatology and Venereology, Pomeranian Medical University, Siedlecka 2, 72-010, Police, Poland.
Pomeranian Medical University · PLProvidence College · USUniversity of Szczecin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive research has found strongly increased generation of reactive oxygen species, free radicals, and reactive nitrogen species during acute physical exercise that can lead to oxidative stress (OS) and impair muscle function. Polyphenols (PCs), the most abundant antioxidants in the human diet, are of increasing interest to athletes as antioxidants. Current literature suggests that antioxidants supplementation can effectively modulate these processes. This overview summarizes the actual knowledge of chemical and biomechanical properties of PCs and their impact as supplements on acute exercise-induced OS, inflammation control, and exercise performance. Evidence maintains that PC supplements have high potency to positively impact redox homeostasis and improve skeletal muscle's physiological and physical functions. However, many studies have failed to present improvement in physical performance. Eleven of 15 representative experimental studies reported a reduction of severe exercise-induced OS and inflammation markers or enhancement of total antioxidant capacity; four of eight studies found improvement in exercise performance outcomes. Further studies should be continued to address a safe, optimal PC dosage, supplementation timing during a severe training program in different sports disciplines, and effects on performance response and adaptations of skeletal muscle to exercise.

Indexed as

AntioxidantsOxidative StressDietary SupplementsExerciseHumansInflammationMuscle, SkeletalAntioxidantsAntioxidant activityAthletic performanceOxidative stressPhysical exercisePolyphenolsSupplementation

Identifiers

PMID35931969
PMCPMC10717775
OpenAlexW4289884286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.