Evidence map›Paper›PMID 35931953›Full record

ArticleBMC infectious diseases2022

Facilitators for retaining men who have sex with men in pre-exposure prophylaxis care in real world clinic settings within the United States.

Brooke G Rogers, C Sosnowy, A Zanowick-Marr, P A Chan, L A Mena, R R Patel, W C Goedel, T Arnold, C Chu, D Galipeau and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Brooke G RogersDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA. brooke_rogers@brown.edu.
C SosnowyDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
A Zanowick-MarrDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
P A ChanDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
L A MenaDepartment of Population Health Science, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
R R PatelDepartment of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, 63110, USA.
W C GoedelDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, 02903, USA.
T ArnoldDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, 02903, USA.
C ChuDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
D GalipeauDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
M C MontgomeryDepartment of Medicine, Division of Infectious Diseases, Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
K CuroeDepartment of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, 63110, USA.
A UnderwoodDepartment of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, 63110, USA.
J VillalobosDepartment of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, 63110, USA.
C GomilliaDepartment of Population Health Science, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
A S NunnDepartment of Social and Behavioral Sciences, Brown University School of Public Health, Providence, RI, 02903, USA. amy_nunn@brown.edu.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Characterizing the HIV pre-exposure prophylaxis care continuum for African American and Hispanic/Latino men who have sex with menR01MH114657 · NIMH · MIRIAM HOSPITAL · PI CHAN, PHILIP ANDREW, NUNN, AMY STEWART · 2017 to 2021
$3.4M
Improving HIV Prevention Through a Psychological Flexibility-Based ApproachK23MH124539 · NIMH · RHODE ISLAND HOSPITAL · PI ARNOLD, TRISHA · 2021 to 2025
$969k
National Institutes of Mental Health 5R01MH114657-02National Institutes of Mental Health R25MH083620NIAID NIH HHS P30 AI042853NIMH NIH HHS K23 MH124539NIMH NIH HHS K23MH124539-01A1NIMH NIH HHS L30 MH123946NIMH NIH HHS R01 MH114657NIMH NIH HHS R25 MH083620Providence/Boston Center for AIDS Research P30AI042853
6 · The paper itself

Abstract

backgroundPre-exposure prophylaxis (PrEP) can significantly reduce HIV acquisition especially among communities with high HIV prevalence, including men who have sex with men (MSM). Much research has been finding suboptimal PrEP persistence; however, few studies examine factors that enhance PrEP persistence in real-world settings.

methodsWe interviewed 33 patients who identified as MSM at three different PrEP clinics in three regions of the U.S. (Northeast, South, Midwest). Participants were eligible if they took PrEP and had been retained in care for a minimum of 6 months. Interviews explored social, structural, clinic-level and behavioral factors that influencing PrEP persistence.

resultsThrough thematic analysis we identified the following factors as promoting PrEP persistence: (1) navigation to reduce out-of-pocket costs of PrEP (structural), (2) social norms that support PrEP use (social), (3) access to LGBTQ + affirming medical providers (clinical), (4) medication as part of a daily routine (behavioral), and (5) facilitation of sexual health agency (belief). DISCUSSION: In this sample, persistence in PrEP care was associated with structural and social supports as well as a high level of perceived internal control over protecting their health by taking PrEP. Patients might benefit from increased access, LGBTQ + affirming medical providers, and communications that emphasize PrEP can promote sexual health.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesAmbulatory Care FacilitiesHomosexuality, MaleHumansMaleUnited StatesAnti-HIV AgentsMedication adherencePersistencePre-exposure prophylaxisPrEP continuumRetention in care

Identifiers

PMID35931953
PMCPMC9354303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.