Evidence map›Paper›PMID 35931925›Full record

ArticleAmerican journal of clinical dermatology2022

Curbing COVID-19 Vaccine Hesitancy from a Dermatological Standpoint: Analysis of Cutaneous Reactions in the Vaccine Adverse Event Reporting System (VAERS) Database.

Julianne M Falotico, Amar D Desai, Asghar Shah, Jose W Ricardo, Shari R Lipner

Abstract read
In one paragraph

Article in American journal of clinical dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julianne M FaloticoRenaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0001-5068-6803
Amar D DesaiRutgers New Jersey Medical School, Newark, NJ, USA.ORCID http://orcid.org/0000-0001-6873-3217
Asghar ShahBrown University, Providence, RI, USA.
Jose W RicardoDepartment of Dermatology, Weill Cornell Medicine, 1305 York Avenue, New York, NY, 10021, USA.ORCID http://orcid.org/0000-0002-8355-4193
Shari R LipnerDepartment of Dermatology, Weill Cornell Medicine, 1305 York Avenue, New York, NY, 10021, USA. shl9032@med.cornell.edu.ORCID http://orcid.org/0000-0001-5913-9304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAdverse reactions to the COVID-19 vaccines have been of interest since their emergency authorization. Cutaneous manifestations of the vaccines are not well studied. We aimed to characterize cutaneous reactions to the Moderna (mRNA-1273) and the Pfizer-BioNTech (BNT162b2) COVID-19 vaccines on a large, national scale.

methodsThe Vaccine Adverse Event Reporting System was filtered for cutaneous and hair and nail reactions to the COVID-19 vaccines. Patient demographics and past medical histories, vaccine manufacturer and dosing, symptom timing, reaction location, and patient outcomes were extracted from each report.

resultsAs of December 24, 2021, there were 67,273 cutaneous reactions to all COVID-19 vaccines, with most patients receiving the Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) vaccines. The most common reactions overall were injection-site reaction, urticaria, and papular rash, with injection-site reaction more common after the Moderna (mRNA-1273) vaccine, and all other cutaneous reactions more common after the Pfizer-BioNTech (BNT162b2) vaccine. Patients with past histories of psoriasis, urticaria, and local site reactions to a vaccine were more likely to report these same symptoms after the COVID-19 vaccine.

conclusionPatients should be counseled about these potential dermatologic reactions to the COVID-19 vaccines. Most occur within the first few days after vaccination, and are mild and self-limiting. Patients should therefore be encouraged that it is safe to receive the COVID-19 vaccine from a dermatological perspective.

Indexed as

COVID-19COVID-19 VaccinesUrticariaVaccines2019-nCoV Vaccine mRNA-1273Adverse Drug Reaction Reporting SystemsBNT162 VaccineHumansVaccination Hesitancy2019-nCoV Vaccine mRNA-1273BNT162 VaccineCOVID-19 VaccinesVaccines

Identifiers

PMID35931925
PMCPMC9361907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.