Evidence map›Paper›PMID 35931916›Full record

ArticleJournal of racial and ethnic health disparities2023

The Role of Transportation in the Enrollment of Elderly African Americans into Exercise and Memory Study: GEMS Study.

Lennox Graham, Julius Ngwa, Oyonumo Ntekim, Oludolapo Ogunlana, Steven Johnson, Sheeba Nadarajah, Thomas V Fungwe, Jillian Turner, Mara Ramirez Ruiz, Javed Khan and 1 more

Abstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lennox GrahamDepartment of Health Management, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, 20059, USA.
Julius NgwaDivision of Cardiovascular Medicine, College of Medicine, Howard University, Washington, DC, 20059, USA.
Oyonumo NtekimDepartment of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, 20059, USA.
Oludolapo OgunlanaDepartment of Medicine and Clinical Translational Science Program, Division of Geriatrics, Howard University Hospital, 2041 Georgia Ave NW, Washington, DC, 20060, USA.
Steven JohnsonDepartment of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, 20059, USA.
Sheeba NadarajahDepartment of Nursing, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, 20059, USA.
Thomas V FungweDepartment of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, 20059, USA.
Jillian TurnerDepartment of Medicine and Clinical Translational Science Program, Division of Geriatrics, Howard University Hospital, 2041 Georgia Ave NW, Washington, DC, 20060, USA.
Mara Ramirez RuizDepartment of Medicine and Clinical Translational Science Program, Division of Geriatrics, Howard University Hospital, 2041 Georgia Ave NW, Washington, DC, 20060, USA.
Javed KhanDepartment of Medicine and Clinical Translational Science Program, Division of Geriatrics, Howard University Hospital, 2041 Georgia Ave NW, Washington, DC, 20060, USA.
Thomas O ObisesanDepartment of Medicine and Clinical Translational Science Program, Division of Geriatrics, Howard University Hospital, 2041 Georgia Ave NW, Washington, DC, 20060, USA. tobisesan@howard.edu.

Funding

Genes, Exercise, Neurocognitive and Neurodegeneration: Community-Based ApproachR01AG045058 · NIA · HOWARD UNIVERSITY · PI OBISESAN, THOMAS O · 2014 to 2018
$2.9M
Effects of Standardized Aerobic Exercise-Training on Neurocognitive and NeurodegeR01AG031517 · NIA · HOWARD UNIVERSITY · PI OBISESAN, THOMAS O · 2009 to 2010
$2.0M
NIA NIH HHS R01 AG031517NIA NIH HHS R01 AG045058
6 · The paper itself

Abstract

backgroundUnderstanding the factors driving recruitment and enrollment of African Americans (AA)s in clinical translational research will assure that underrepresented populations benefit from scientific progress and new developments in the diagnosis and treatment of Alzheimer's disease and related disorders. While transportation is pivotal to volunteers' ability to participate in research, its contribution to enrollment in exercise studies on AD is yet to be elucidated. Thus, this research focuses on identifying factors that influence the recruitment and enrollment of African Americans in biomedical studies and determining whether the availability of transportation motivates participation in time-demanding exercise studies on AD.

methodsWe analyzed recruitment data collected from 567 volunteers ages 55 and older screened through various recruitment sources and considered for enrollment in our exercise and memory study. To determine whether transportation influenced the enrollment of African Americans (AA)s in biomedical studies, multiple logistic regression analysis was performed to identify significant factors that drive enrollment. Furthermore, the association of race and demographic factors on the availability of transportation was assessed.

resultsDemographic factors, age at screening, education, gender, and cognitive scores were not significantly different among those enrolled compared to control (not-enrolled). In the relationship of enrollment to transportation, enrolled participants were more likely to have access to transportation (79.12%) than not-enrolled participants who had less access to transportation (71.6%); however, the association was not statistically significant. However, race differentially influenced the likelihood of enrollment, with elderly AAs being significantly less likely to have transportation (p = 0.020) than the Whites but more likely than "others" to have transportation.

conclusionOur findings suggest that access to transportation may be a key factor motivating enrollment in an exercise and memory study in a predominantly AA sample. Notably, AAs in our sample were less likely to have transportation than Whites. Other demographic factors and cognitive scores did not significantly influence enrollment in our sample. A larger sample and more detailed assessment of transportation are needed to further discern the role of transportation in clinical trials.

Indexed as

Black or African AmericanClinical Trials as TopicPatient ParticipationTransportation of PatientsWhiteAgedEducational StatusExerciseHealth Services AccessibilityHumansMemoryMiddle AgedAfrican AmericansClinical researchExerciseMemoryMini–Mental State ExaminationRecruitmentTransportation

Identifiers

PMID35931916
PMCPMC10322752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.