ArticleInternational orthopaedics2022
Safety and efficacy of negative pressure wound therapy in treating deep surgical site infection after lumbar surgery.
Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 5 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Risk factors for surgical site infections after orthopaedic surgery: A meta-analysis and systematic review.International wound journal · 2025Pooled it
- Effectiveness of negative pressure wound therapy in treating deep surgical site infections after spine surgery: a meta-analysis of single-arm studies.Journal of orthopaedic surgery and research · 2025Pooled it
- Effect of negative pressure wound therapy on the incidence of deep surgical site infections after orthopedic surgery: a meta-analysis and systematic review.Journal of orthopaedic surgery and research · 2024Pooled it
- Influence of closed-incision negative-pressure wound therapy on the incidence of surgical site wound infection in patients undergoing spine surgery: A meta-analysis.International wound journal · 2023Pooled it
- Impact of negative pressure wound treatment on incidence of surgical site infection in varied orthopedic surgeries: A systematic review and meta-analysis.International wound journal · 2023Pooled it
- Recommendations of the International Consensus Meeting (ICM) 2025 on Spinal Infections: Part A Pyogenic Spondylodiscitis.Global spine journal · 2026Article
- Negative Pressure Wound Therapy Modulates Wound pH and Bacterial Invasion inPlastic and reconstructive surgery. Global open · 2026Article
- Successful treatment of a non-healing lumbar incision post-radiotherapy using vacuum sealing drainage: A case report.World journal of orthopedics · 2025Article
- Infective Spondylitis in Adults: A Journey Through Diagnosis, Management, and Future Directions.Antibiotics (Basel, Switzerland) · 2025Review
- Treatment of refractory thoracolumbar spine infection by thirteen times of vacuum sealing drainage: A case report.World journal of orthopedics · 2025Article
- Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm.Global spine journal · 2025Article
- Investigating the efficacy of vacuum sealing drainage versus traditional negative pressure drainage in treating deep incision infections following posterior cervical internal fixation-a retrospective cohort study.European journal of medical research · 2024Article
- RETRACTED: Effects of negative-pressure wound therapy in the prevention of surgical-site wound infection after vascular surgery: A meta-analysis.International wound journal · 2024Article
- Investigating the feasibility and effectiveness of bacterial culture in negative pressure wound drainage fluid.Frontiers in medicine · 2024Article
- Article
- Case Report: A spinal infection with bilateral psoas abscesses was treated with NPWT to enhance the local infection by increasing the infiltration of neutrophil cells and draining the pus.Frontiers in cellular and infection microbiology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the efficacy and safety of negative pressure wound therapy (NPWT) for post-operative deep surgical site infection (SSI) after posterior instrumented spinal surgery.
methodsWe retrospectively compared the clinical outcomes of NPWT with standard debridement for deep SSI after posterior instrumented spinal surgery from 2012 to 2020 in our department. The primary outcomes were peri-operative characteristics including positive organism results, duration of fever, and visual analogue scale (VAS) pain scores three days after re-operation. The secondary outcomes were post-operative characteristics including implant infection recurrence, implant retention rate, duration of hospitalization, and VAS at discharge. Pearson's chi-squared analysis (categorical) and Student's t test (continuous) were used to determine the differences.
resultsThirty-four patients were included, of which 19 underwent NPWT, and 15 underwent standard debridement. Patients in the NPWT group all significantly improved primary outcomes including duration of fever after re-operation (0.95 ± 1.13 vs 4.07 ± 5.35, P = 0.001), positive organism results (14 of 19 vs 2 of 15, P < 0.01), and VAS at 3 days after re-operation (2.58 ± 0.69 vs 3.40 ± 1.06, P < 0.05). Patients in NPWT group exhibited significant decrease in implant infection recurrence (0 of 19 vs 5 of 15, P < 0.01), implant retention rate (19 of 19 vs 10 of 15, P < 0.01), duration of hospitalization (27.74 ± 10.95 vs 37.67 ± 13.67, P < 0.01).
conclusionsNPWT is a feasible and safe treatment option for deep SSI after posterior instrumented spinal surgery.
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