Evidence map›Paper›PMID 35931736›Full record

ArticleExperimental & molecular medicine2022

Akt1-dependent expression of angiopoietin 1 and 2 in vascular smooth muscle cells leads to vascular stabilization.

Jung Min Ha, Seo Yeon Jin, Hye Sun Lee, Hye Jin Kum, Farzaneh Vafaeinik, Hong Koo Ha, Sang Heon Song, Chi Dae Kim, Sun Sik Bae

Open access · goldAbstract read
In one paragraph

Article in Experimental & molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Role of Tie-2 Axis in Sepsis: A Potential Therapeutic Target.Journal of cellular and molecular medicine · 2025
    Review
  8. Article
  9. Signaling Role of Pericytes in Vascular Health and Tissue Homeostasis.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jung Min HaGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Seo Yeon JinGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Hye Sun LeeGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Hye Jin KumGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Farzaneh VafaeinikGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Hong Koo HaDepartment of Urology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.ORCID http://orcid.org/0000-0002-8240-7765
Sang Heon SongDepartment of Internal Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Chi Dae KimGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Sun Sik BaeGene and Cell Therapy Research Center for Vessel-Associated Disease, Medical Research Institute, and Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea. sunsik@pusan.ac.kr.ORCID http://orcid.org/0000-0002-1027-6639
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal angiogenesis was delayed in VSMC-specific Akt1-deficient mice (Akt1

Indexed as

Muscle, Smooth, VascularAngiopoietin-1Angiopoietin-2AnimalsMiceMyocytes, Smooth MusclePericytesProto-Oncogene Proteins c-aktSignal TransductionAkt1 protein, mouseAngiopoietin-1Angiopoietin-2Angpt1 protein, mouseAngpt2 protein, mouseProto-Oncogene Proteins c-akt

Identifiers

PMID35931736
PMCPMC9440121
OpenAlexW4289885511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.