Evidence map›Paper›PMID 35931692›Full record

ArticleNature communications2022

Mettl3-mediated mRNA m

Yan Xu, Zhuowei Zhou, Xinmei Kang, Lijie Pan, Chang Liu, Xiaoqi Liang, Jiajie Chu, Shuai Dong, Yanli Li, Qiuli Liu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

  1. Dysregulated mScience advances · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. METTL3-driven mFrontiers in immunology · 2026
    Article
  6. Review
  7. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  8. YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
  10. Article
  11. METTL14-Induced MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Epitranscriptomic RNA mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yan Xu *Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-5653-291X
Zhuowei Zhou *Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-9413-336X
Xinmei Kang *Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Lijie PanBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chang LiuBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaoqi LiangBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jiajie ChuBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shuai DongBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yanli LiBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Qiuli LiuBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yuetong SunBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shanshan YuBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Qi ZhangBiotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. zhangq27@mail.sysu.edu.cn.ORCID 0000-0001-9916-8919
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic specification and functional maturation are tightly controlled throughout development. N6-methyladenosine (m

Indexed as

MethyltransferasesTranscription FactorsAdenosineAnimalsHepatocyte Nuclear Factor 4LiverMiceRNA, MessengerAdenosineHepatocyte Nuclear Factor 4Hnf4a protein, mouseMethyltransferasesMettl3 protein, mouseRNA, MessengerTranscription Factors

Identifiers

PMID35931692
PMCPMC9355946
OpenAlexW4289874680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.