Evidence map›Paper›PMID 35931639›Full record

ReviewTrends in parasitology2022

Making sense of sensory behaviors in vector-borne helminths.

Nicolas J Wheeler, Elissa A Hallem, Mostafa Zamanian

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in parasitology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. A high-throughput sensory assay for parasitic and free-living nematodes.Integrative biology : quantitative biosciences from nano to macro · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicolas J WheelerDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA.
Elissa A HallemDepartment of Microbiology, Immunology & Molecular Genetics and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA.
Mostafa ZamanianDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: mzamanian@wisc.edu.
University of Wisconsin–Madison · USUniversity of California, Los Angeles · US

Funding

Chemosensation in skin-penetrating parasitic nematodesR01DC017959 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HALLEM, ELISSA ANYON · 2019 to 2023
$2.6M
Molecular mechanisms controlling secretion in filarial nematode parasitesR01AI151171 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Mostafa Zamanian · 2020 to 2026
$2.4M
Determining the molecular basis of chemosensory behaviors in mosquito-borne filarial nematode parasitesF32AI152347 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WHEELER, NICOLAS J · 2021 to 2022
$121k
Howard Hughes Medical InstituteNIAID NIH HHS F32 AI152347NIAID NIH HHS R01 AI151171NIDCD NIH HHS R01 DC017959Wellcome Trust
6 · The paper itself

Abstract

Migrations performed by helminths are impressive and diverse, and accumulating evidence shows that many are controlled by sophisticated sensory programs. The migrations of vector-borne helminths are particularly complex, requiring precise, stage-specific regulation. We review the contrasting states of knowledge on snail-borne schistosomes and mosquito-borne filarial nematodes. Rich observational data exist for the chemosensory behaviors of schistosomes, while the molecular sensory pathways in nematodes are well described. Recent investigations on the molecular mechanisms of sensation in schistosomes and filarial nematodes have revealed some features conserved within their respective phyla, but adaptations correlated with parasitism are pronounced. Technological developments are likely to extend these advances, and we forecast how these technologies may be applied.

Indexed as

CulicidaeHelminthsNematodaAnimalsDisease VectorsMosquito Vectorschemoreceptorschemosensationsensory behaviorsvector-borne helminths

Identifiers

PMID35931639
PMCPMC9481669
OpenAlexW4289528288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.