Evidence map›Paper›PMID 35931470›Full record

ArticleTransplantation proceedings

Mortality Due to COVID-19 in Renal Transplant Recipients, Related to Variants of SARS-CoV-2 and Vaccination in Mexico.

Juan Carlos H Hernández Rivera, Mariana Salazar Mendoza, Luis García Covarrubias, Ana Laura Quiroz Ramírez, Lizbeth Chicas Reyes, Manuel Bautista Hernández, Jorge Romero Martínez, Yohaheri Pineda Contla, Julissa Madai Velasco Durán, Agustín Trejo Rivas and 3 more

Open access · greenAbstract read
In one paragraph

Article in Transplantation proceedings. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Juan Carlos H Hernández RiveraNephrological Diseases Medical Research Unit, Hospital de Especialidades Centro Médico Nacional Siglo XXI, IMSS, CdMx. Electronic address: juancarloshhernandezrivera@hotmail.com.
Mariana Salazar MendozaCoronary Unit, Regional Hospital "Lic. Adolfo López Mateos", ISSSTE, CdMx.
Luis García CovarrubiasRenal Transplant Unit, General Hospital of Mexico, CdMx, Mexico; Surgery Service, Hospital General de Mexico, CdMx.
Ana Laura Quiroz RamírezSuperior School of Medicine, National Polytechnic Institute, CdMx.
Lizbeth Chicas ReyesSuperior School of Medicine, National Polytechnic Institute, CdMx.
Manuel Bautista HernándezSuperior School of Medicine, National Polytechnic Institute, CdMx.
Jorge Romero MartínezSuperior School of Medicine, National Polytechnic Institute, CdMx.
Yohaheri Pineda ContlaSuperior School of Medicine, National Polytechnic Institute, CdMx.
Julissa Madai Velasco DuránSuperior School of Medicine, National Polytechnic Institute, CdMx.
Agustín Trejo RivasSuperior School of Medicine, National Polytechnic Institute, CdMx.
Samantha Lorelae Rodríguez FloresSuperior School of Medicine, National Polytechnic Institute, CdMx.
Walter Adolfo Querevalú MurilloHospital coordination of organ and tissue donation for transplant purposes, Hospital de Especialidades Centro Médico Nacional Siglo XXI, IMSS, CdMx.
José Ramón Paniagua SierraNephrological Diseases Medical Research Unit, Hospital de Especialidades Centro Médico Nacional Siglo XXI, IMSS, CdMx.
National Polytechnic School · ECCentro Medico Nacional Siglo XXI · MXHospital General de México · MXInstitute for Social Security and Services for State Workers · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSARS-CoV-2 infection in transplant patients has shown greater lethality and vaccination in this group of patients has shown less information. The objective of this study is to show the statistics in Mexico of lethality in kidney recipients infected with COVID-19 in relation to vaccination and variants of the coronavirus.

methodsThis is a bibliographic search of kidney transplant recipient patients since the start of the pandemic in Mexico to determine lethality after SARS-CoV-2 compared to the general population and in relation to patients, the 4 most important infectious peaks in the country due to identified variants, and also before and after vaccination.

resultsThe global lethality is 26.91% from the beginning of the pandemic to April 9, 2022 in kidney recipients in Mexico (130 deaths of 483 infected kidney transplant recipients) compared to the national lethality of 5.60%. Variant B. 1.1.220 represented the highest lethality with 30.43% and the lowest lethality was Omicron with 16.41%. The lethality prior to vaccination was 30.94% and 23.46% after it.

conclusionBoth some variants and vaccination have influenced a lower lethality due to COVID-19 in Mexico in kidney transplant patients; It is important to consider global recommendations, such as a third or fourth dose, a combination of mRNA vaccines and vectors in order to reduce lethality in this group of patients.

Indexed as

COVID-19Kidney TransplantationHumansKidneyMexicoSARS-CoV-2Transplant RecipientsVaccination

Identifiers

PMID35931470
PMCPMC9156950
OpenAlexW4281774142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.