Evidence map›Paper›PMID 35931371›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Epidemiological assessment of SARS-CoV-2 reinfection.

Marwa Almadhi, Adel Salman Alsayyad, Ronan Conroy, Stephen Atkin, Abdulla Al Awadhi, Jaffar A Al-Tawfiq, Manaf AlQahtani

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  12. Reinfections from SARS-CoV-2: A Retrospective Study from the Gyncentrum Genetic Laboratory in Sosnowiec, Poland, April 2020 to July 2022.Medical science monitor : international medical journal of experimental and clinical research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Marwa AlmadhiNational Taskforce for Combating the Coronavirus (COVID-19), Supreme health council, Manama, Bahrain; University of Manchester, Manchester, UK.
Adel Salman AlsayyadDepartment of Family and Community Medicine, Arabian Gulf University, Manama, Bahrain.
Ronan ConroyRoyal College of Surgeons in Ireland, Dublin, Ireland.
Stephen AtkinRoyal College of Surgeons in Ireland, Busaiteen, Bahrain.
Abdulla Al AwadhiNational Taskforce for Combating the Coronavirus (COVID-19), Supreme health council, Manama, Bahrain; Bahrain Defence Force Hospital, Riffa, Bahrain.
Jaffar A Al-TawfiqInfectious Disease Unit, Specialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA; Division of Infectious Diseases, Johns Hopkins University, Baltimore, Maryland, USA.
Manaf AlQahtaniNational Taskforce for Combating the Coronavirus (COVID-19), Supreme health council, Manama, Bahrain; Royal College of Surgeons in Ireland, Busaiteen, Bahrain; Bahrain Defence Force Hospital, Riffa, Bahrain. Electronic address: mqahtani@rcsi-mub.com.
Royal College of Surgeons in Ireland - Bahrain · BHArabian Gulf University · BHBahrain Center for Strategic International and Energy Studies · BHJohns Hopkins University · USRoyal College of Surgeons in Ireland · IEUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSARS-CoV-2 vaccination has been shown to reduce infection severity; however, the reinfection frequency among unvaccinated, partially vaccinated, and fully vaccinated individuals remains unclear. This study aims to elucidate the rates of and factors associated with such occurrences.

methodsThis retrospective epidemiological report included 1362 COVID-19 reinfection cases in Bahrain between April 2020 and July 2021. We analyzed differences in disease severity and reinfection characteristics among various vaccination statuses: fully vaccinated, interrupted vaccination, one-dose vaccination, postreinfection vaccination, and unvaccinated.

resultsReinfection cases increased from zero per month in April-June 2020 to a sharp peak of 579 in May 2021. A significantly larger proportion of reinfected individuals were male (60.3%, P <0.0001). Reinfection episodes were highest among those 30-39 years of age (29.7%). The fewest reinfection episodes occurred at 3-6 months after the first infection (20.6%) and most occurred ≥9 months after the initial infection (46.4%). Most individuals were asymptomatic during both episodes (35.7%). Reinfection disease severity was mild, with vaccinated patients less likely to have symptomatic reinfection (odds ratio 0.71, P = 0.004). Only 6.6% of reinfected patients required hospitalization. One death was recorded; the patient belonged to the unvaccinated group.

conclusionVaccine-induced immunity and previous infection with or without vaccination were effective in reducing reinfection disease severity.

Indexed as

COVID-19SARS-CoV-2COVID-19 VaccinesFemaleHumansMaleReinfectionRetrospective StudiesCOVID-19 VaccinesCovid-19Public healthReinfectionSARS-CoV-2Vaccination

Identifiers

PMID35931371
PMCPMC9345650
OpenAlexW4289526046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.