Evidence map›Paper›PMID 35931306›Full record

ArticleNeuroImage2022

Estimating axial diffusivity in the NODDI model.

Amy Fd Howard, Michiel Cottaar, Mark Drakesmith, Qiuyun Fan, Susie Y Huang, Derek K Jones, Frederik J Lange, Jeroen Mollink, Suryanarayana Umesh Rudrapatna, Qiyuan Tian and 2 more

Abstract read
In one paragraph

Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amy Fd HowardFMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom. Electronic address: amy.howard@ndcn.ox.ac.uk.
Michiel CottaarFMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Mark DrakesmithCardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, United Kingdom; Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Qiuyun FanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States; Harvard Medical School, Boston, Massachusetts, United States; Department of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, China; Academy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, China.
Susie Y HuangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States; Harvard Medical School, Boston, Massachusetts, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Derek K JonesCardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, United Kingdom; Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Frederik J LangeFMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Jeroen MollinkFMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Suryanarayana Umesh RudrapatnaCardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, United Kingdom; Philips Innovation Campus, Bangalore, India.
Qiyuan TianAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States; Harvard Medical School, Boston, Massachusetts, United States.
Karla L MillerFMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Saad JbabdiFMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

Funding

CONNECTOME 2.0: DEVELOPING THE NEXT GENERATION HUMAN MRI SCANNER FOR BRIDGING STUDIES OF THE MICRO-, MESO- AND MACRO-CONNECTOMEU01EB026996 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BASSER, PETER J., HUANG, SUSIE YI · 2018 to 2022
$14.2M
Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BRUCE R ROSEN · 2020 to 2026
$10.9M
Toward a Validated in Vivo Imaging Marker of Axonal Damage Predictive of Progressive Disability in Multiple SclerosisR01NS118187 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI · 2021 to 2025
$2.8M
Characterizing axonal damage in multiple sclerosis using TractCaliber MRIK23NS096056 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HUANG, SUSIE YI · 2016 to 2020
$877k
Advancing methods for mapping short-range association fibers in the aging brainK99AG073506 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI TIAN, QIYUAN · 2021 to 2022
$268k
Medical Research Council MR/L009013/1NIA NIH HHS K99 AG073506NIBIB NIH HHS P41 EB030006NIBIB NIH HHS U01 EB026996NINDS NIH HHS K23 NS096056NINDS NIH HHS R01 NS118187Wellcome Trust 096646/Z/11/ZWellcome Trust 104943/Z/14/ZWellcome Trust 202788/Z/16/ZWellcome Trust 203139/Z/16/ZWellcome Trust WT202788/Z/16/AWellcome Trust WT215573/Z/19/ZWellcome Trust WT221933/Z/20/Z
6 · The paper itself

Abstract

To estimate microstructure-related parameters from diffusion MRI data, biophysical models make strong, simplifying assumptions about the underlying tissue. The extent to which many of these assumptions are valid remains an open research question. This study was inspired by the disparity between the estimated intra-axonal axial diffusivity from literature and that typically assumed by the Neurite Orientation Dispersion and Density Imaging (NODDI) model (d

Indexed as

NeuritesWhite MatterAxonsBrainDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansAxial diffusivityDiffusion MRIHigh b-valueNODDIOrientation dispersionWhite matter

Identifiers

PMID35931306
PMCPMC9802007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.