Evidence map›Paper›PMID 35931075›Full record

ArticleStem cell reports2022

Direct visualization of the transition status during neural differentiation by dual-fluorescent reporter human pluripotent stem cells.

Gwanghyun Park, Minkyung Shin, Wonyoung Lee, Akitsu Hotta, Taeko Kobayashi, Yoichi Kosodo

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Lamin B1 as a key modulator of the developing and aging brain.Frontiers in cellular neuroscience · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gwanghyun ParkKorea Brain Research Institute (KBRI), Daegu 41068, Republic of Korea.
Minkyung ShinKorea Brain Research Institute (KBRI), Daegu 41068, Republic of Korea.
Wonyoung LeeKorea Brain Research Institute (KBRI), Daegu 41068, Republic of Korea.
Akitsu HottaCenter for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
Taeko KobayashiResearch Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.
Yoichi KosodoKorea Brain Research Institute (KBRI), Daegu 41068, Republic of Korea. Electronic address: kosodo@kbri.re.kr.
Korea Brain Research Institute · KRKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human induced pluripotent stem cells (hiPSCs) can differentiate into neurons and glia via neural progenitor cells and are widely used for neurogenic studies. However, directly visualizing the transition status during the neural differentiation of live cells is difficult. Here, targeting NEUROG2 (NGN2) and TUBB3 as markers of neurogenic cells and neurons, respectively, we established TUBB3

Indexed as

Induced Pluripotent Stem CellsNeural Stem CellsAnimalsBasic Helix-Loop-Helix ProteinsCell DifferentiationHumansMiceNerve Tissue ProteinsNeuronsOrganoidsBasic Helix-Loop-Helix ProteinsNerve Tissue ProteinsNeurog2 protein, mousebrain organoidsCRISPR-Cas9genome editionhuman iPSCslive imagingNEUROG2REELINtransplantationTUBB3

Identifiers

PMID35931075
PMCPMC9481873
OpenAlexW4289835747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.