Evidence map›Paper›PMID 35930748›Full record

ArticleBlood2022

Prebiotic galactooligosaccharides interact with mouse gut microbiota to attenuate acute graft-versus-host disease.

Zachary C Holmes, Helen Tang, Congxiao Liu, Amy Bush, Benjamin C Neubert, Yiqun Jiao, Megan Covington, Diana M Cardona, Michelle C Kirtley, Benny J Chen and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Blood, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06802406 (Nutrition OUtReach In Systems of Healthcare), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06802406 narecruitingnot on this mapstarted 2025, after this paper: background citation

Nutrition OUtReach In Systems of Healthcare

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2029Enrolled210ConditionsALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Autologous Haemopoietic Stem Cell Transplant, CAR-T Cell Therapy, Food InsecurityArmsFood Bags
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Gut microbiota and acute graft-versus-host disease.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Graft-Versus-Host Disease Mouse Models: A Clinical-Translational Perspective.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zachary C HolmesDepartment of Molecular Genetics and Microbiology, Duke University, Durham, NC.ORCID 0000-0002-2733-265X
Helen TangDuke University School of Medicine, Durham, NC.ORCID 0000-0001-8528-1435
Congxiao LiuDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.
Amy BushDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0002-4495-3765
Benjamin C NeubertProgram in Computational Biology and Bioinformatics, Duke University, Durham, NC.ORCID 0000-0002-3819-4803
Yiqun JiaoDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.
Megan CovingtonDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.
Diana M CardonaDepartment of Pathology, Duke University, Durham, NC.
Michelle C KirtleyDepartment of Molecular Genetics and Microbiology, Duke University, Durham, NC.
Benny J ChenDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0003-4588-3890
Nelson J ChaoDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0001-6725-7220
Lawrence A DavidDepartment of Molecular Genetics and Microbiology, Duke University, Durham, NC.
Anthony D SungDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC.

Funding

Personalizing prebiotic therapies that target human gut microbiotaR01DK116187 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2018 to 2026
$3.7M
Using DNA sequencing to assess dietary species richnessR01DK128611 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2022 to 2026
$2.9M
NIDDK NIH HHS R01 DK116187NIDDK NIH HHS R01 DK128611
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeGraft vs Host DiseaseAnimalsMicePrebioticsPrebiotics

Identifiers

PMID35930748
PMCPMC10653043

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.