Evidence map›Paper›PMID 35930707›Full record

ArticleAdvanced healthcare materials2022

Engineered Exosomes Containing Cathelicidin/LL-37 Exhibit Multiple Biological Functions.

Yajuan Su, Navatha Shree Sharma, Johnson V John, Gitali Ganguli-Indra, Arup K Indra, Adrian F Gombart, Jingwei Xie

Open access · hybridAbstract read
In one paragraph

Article in Advanced healthcare materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Extracellular Vesicle-Based Hydrogels for Wound Healing Applications.International journal of molecular sciences · 2023
    Review
  9. Bioengineered MSC-derived exosomes in skin wound repair and regeneration.Frontiers in cell and developmental biology · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yajuan SuDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.
Navatha Shree SharmaDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.
Johnson V JohnDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.
Gitali Ganguli-IndraDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, 97331, USA.
Arup K IndraDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, 97331, USA.
Adrian F GombartLinus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, 97331, USA.
Jingwei XieDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.ORCID 0000-0002-8126-1397
Nebraska Medical Center · USOregon State University · USUniversity of Nebraska–Lincoln · US

Funding

Nanofiber-based Delivery of Combined Immune-modulating Compounds to Minimize Infection and Enhance Wound HealingR01GM123081 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI XIE, JINGWEI · 2017 to 2024
$2.8M
NIGMS NIH HHS R01 GM123081
6 · The paper itself

Abstract

Exosomes show great potential in diagnostic and therapeutic applications. Inspired by the human innate immune defense, herein, we report engineered exosomes derived from monocytic cells treated with immunomodulating compounds 1α,25-dihydroxyvitamin D

Indexed as

ExosomesAntimicrobial Cationic PeptidesBiocompatible MaterialsCathelicidinsHumansHuman Umbilical Vein Endothelial CellsVitamin D3 24-HydroxylaseAntimicrobial Cationic PeptidesBiocompatible MaterialsCathelicidinsVitamin D3 24-Hydroxylaseantibacterial propertyengineered exosomesimmunomodulating compoundsnanofiber matriceswound healing

Identifiers

PMID35930707
PMCPMC9588668
OpenAlexW4291286502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.