Evidence map›Paper›PMID 35930594›Full record

ArticleACS synthetic biology2022

Discovery of 8-Hydroxyquinoline as a Histamine Receptor 2 Blocker Scaffold.

Paola L Marquez-Gomez, Nicholas S Kruyer, Sara L Eisen, Lily R Torp, Rebecca L Howie, Elizabeth V Jones, Stefan France, Pamela Peralta-Yahya

Open access · greenAbstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Paola L Marquez-GomezSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Nicholas S KruyerSchool of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Sara L EisenSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Lily R TorpSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Rebecca L HowieSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Elizabeth V JonesSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Stefan FranceSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID 0000-0001-5998-6167
Pamela Peralta-YahyaSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID 0000-0002-0356-2274
Georgia Institute of Technology · US

Funding

Olfactory receptor-based sensors for biomedical applicationsR35GM124871 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI Pamela Peralta-Yahya · 2017 to 2026
$3.6M
NIGMS NIH HHS R35 GM124871
6 · The paper itself

Abstract

Histamine receptor 2 (HR

Indexed as

PhagocytosisReceptors, HistamineAnimalsHumansMammalsMolecular Docking SimulationOxyquinolineOxyquinolineReceptors, Histamine

Identifiers

PMID35930594
PMCPMC9396701
OpenAlexW4289970719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.