Evidence map›Paper›PMID 35930588›Full record

ArticlePloS one2022

Prevalence, risk factors, and cardiovascular disease outcomes associated with persistent blood pressure control: The Jackson Heart Study.

Gabriel S Tajeu, Calvin L Colvin, Shakia T Hardy, Adam P Bress, Bamba Gaye, Byron C Jaeger, Gbenga Ogedegbe, Swati Sakhuja, Mario Sims, Daichi Shimbo and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Social Determinants of Health/Health Equity and Hypertension Prevalence Among Mississippi Adults.International journal of environmental research and public health · 2026
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Gabriel S TajeuDepartment of Health Services Administration and Policy, Temple University, Philadelphia, PA, United States of America.ORCID 0000-0002-9982-5250
Calvin L ColvinDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Shakia T HardyDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Adam P BressDepartment of Population Health Sciences, University of Utah School of Medicine, Salt Lake City, UT, United States of America.
Bamba GayeINSERM, U970, Paris Cardiovascular Research Center, Department of Epidemiology, Paris, France.
Byron C JaegerDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Wake Forest, NC, United States of America.
Gbenga OgedegbeDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, United States of America.
Swati SakhujaDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Mario SimsDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, United States of America.
Daichi ShimboDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, United States of America.
Emily C O'BrienDepartments of Population Health Sciences and Neurology, Duke University School of Medicine, Durham, NC, United States of America.
Tanya M SpruillDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, United States of America.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
University of Alabama at Birmingham · USNew York University · USColumbia University Irving Medical Center · USDélégation Paris 5 · FRDuke University · USJackson Memorial Hospital · USTemple University · USUniversity of Utah · USWake Forest University · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Promoting Academic Workforce Development in Behavioral Medicine and Sleep Disorders ResearchR25HL105444 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Girardin Jean-Louis, Tatjana Rundek · 2010 to 2026
$5.8M
Psychopathology, Disordered Eating, and Impulsivity as Predictors of Outcomes of Bariatric SurgeryR01DK108628 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI SARWER, DAVID B · 2015 to 2019
$2.1M
Machine Learning to Reduce Hypertension Treatment Clinical InertiaK01HL151974 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI TAJEU, GABRIEL S · 2020 to 2024
$739k
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
NCATS NIH HHS KL2 TR001874NCATS NIH HHS UL1 TR001873NHLBI NIH HHS HHSN268201800010INHLBI NIH HHS HHSN268201800011CNHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS K01 HL151974NHLBI NIH HHS K24 HL125704NHLBI NIH HHS R01 HL117323NHLBI NIH HHS R25 HL105444NIDDK NIH HHS R01 DK108628NIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

backgroundMaintaining blood pressure (BP) control over time may contribute to lower risk for cardiovascular disease (CVD) among individuals who are taking antihypertensive medication.

methodsThe Jackson Heart Study (JHS) enrolled 5,306 African-American adults ≥21 years of age and was used to determine the proportion of African Americans that maintain persistent BP control, identify factors associated with persistent BP control, and determine the association of persistent BP control with CVD events. This analysis included 1,604 participants who were taking antihypertensive medication at Visit 1 and had BP data at Visits 1 (2000-2004), 2 (2005-2008), and 3 (2009-2013). Persistent BP control was defined as systolic BP <140 mm Hg and diastolic BP <90 mm Hg at all three visits. CVD events were assessed from Visit 3 through December 31, 2016. Hazard ratios (HR) for the association of persistent BP control with CVD outcomes were adjusted for age, sex, systolic BP, smoking, diabetes, and total and high-density lipoprotein cholesterol at Visit 3.

resultsAt Visit 1, 1,226 of 1,604 participants (76.4%) with hypertension had controlled BP. Overall, 48.9% of participants taking antihypertensive medication at Visit 1 had persistent BP control. After multivariable adjustment for demographic, socioeconomic, clinical, behavioral, and psychosocial factors, and access-to-care, participants were more likely to have persistent BP control if they were <65 years of age, women, had family income ≥$25,000 at each visit, and visited a health professional in the year prior to each visit. The multivariable adjusted HR (95% confidence interval) comparing participants with versus without persistent BP control was 0.71 (0.46-1.10) for CVD, 0.68 (0.34-1.34) for coronary heart disease, 0.65 (0.27-1.52) for stroke, and 0.55 (0.33-0.90) for heart failure.

conclusionLess than half of JHS participants taking antihypertensive medication had persistent BP control, putting them at increased risk for heart failure.

Indexed as

Cardiovascular DiseasesHeart FailureHypertensionAdultAntihypertensive AgentsBlood PressureFemaleHumansLongitudinal StudiesPrevalenceRisk FactorsAntihypertensive Agents

Identifiers

PMID35930588
PMCPMC9355196
OpenAlexW4289986674

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.