Evidence map›Paper›PMID 35930527›Full record

ArticlePloS one2022

Online searches of children's oseltamivir in public primary and specialized care: Detecting influenza outbreaks in Finland using dedicated databases for health care professionals.

Milla Mukka, Samuli Pesälä, Aapo Juutinen, Mikko J Virtanen, Pekka Mustonen, Minna Kaila, Otto Helve

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In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Milla MukkaUniversity of Helsinki, Helsinki, Finland.ORCID 0000-0001-6148-4158
Samuli PesäläUniversity of Helsinki, Helsinki, Finland.ORCID 0000-0002-6090-1367
Aapo JuutinenDepartment of Health Security, Finnish Institute for Health and Welfare, Helsinki, Finland.
Mikko J VirtanenDepartment of Health Security, Finnish Institute for Health and Welfare, Helsinki, Finland.
Pekka MustonenDuodecim Medical Publications Ltd, Helsinki, Finland.
Minna KailaClinicum, University of Helsinki, Helsinki, Finland.
Otto HelveDepartment of Health Security, Finnish Institute for Health and Welfare, Helsinki, Finland.ORCID 0000-0001-6254-3180

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHealth care professionals working in primary and specialized care typically search for medical information from Internet sources. In Finland, Physician's Databases are online portals aimed at professionals seeking medical information. As dosage errors may occur when prescribing medication to children, professionals' need for reliable medical information has increased in public health care centers and hospitals. Influenza continues to be a public health threat, with young children at risk of developing severe illness and easily transmitting the virus. Oseltamivir is used to treat children with influenza. The objective of this study was to compare searches for children's oseltamivir and influenza diagnoses in primary and specialized care, and to determine if the searches could aid detection of influenza outbreaks.

methodsWe compared searches in Physician's Databases for children's oral suspension of oseltamivir (6 mg/mL) for influenza diagnoses of children under 7 years and laboratory findings of influenza A and B from the National Infectious Disease Register. Searches and diagnoses were assessed in primary and specialized care across Finland by season from 2012-2016. The Moving Epidemic Method (MEM) calculated seasonal starts and ends, and paired differences in the mean compared two indicators. Correlation was tested to compare seasons.

resultsWe found that searches and diagnoses in primary and specialized care showed visually similar patterns annually. The MEM-calculated starting weeks in searches appeared mainly in the same week. Oseltamivir searches in primary care preceded diagnoses by -1.0 weeks (95% CI: -3.0, -0.3; p = 0.132) with very high correlation (τ = 0.913). Specialized care oseltamivir searches and diagnoses correlated moderately (τ = 0.667).

conclusionHealth care professionals' searches for children's oseltamivir in online databases linked with the registers of children's influenza diagnoses in primary and specialized care. Therefore, database searches should be considered as supplementary information in disease surveillance when detecting influenza epidemics.

Indexed as

Influenza, HumanOseltamivirAntiviral AgentsChildChild, PreschoolDisease OutbreaksFinlandHealth PersonnelHumansAntiviral AgentsOseltamivir

Identifiers

PMID35930527
PMCPMC9355218

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