Evidence map›Paper›PMID 35930257›Full record

ArticleBiopreservation and biobanking2023

Banking on the Last Gift: Cornell's Signature Program of Postmortem Tissue Procurement.

Susan J Garrison, Lara Mouttham, Marta G Castelhano

Open access · greenAbstract read
In one paragraph

Article in Biopreservation and biobanking, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Susan J GarrisonCornell Veterinary Biobank, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0001-6760-427X
Lara MoutthamCornell Veterinary Biobank, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-1113-9812
Marta G CastelhanoCornell Veterinary Biobank, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0003-2497-1939
Cornell University · US

Funding

The Dog Aging Project: Genetic and Environmental Determinants of Healthy Aging in Companion Dogs Competitive RevisionU19AG057377 · NIA · UNIVERSITY OF WASHINGTON · PI PROMISLOW, DANIEL EDWARD · 2018 to 2023
$29.0M
Developing the Privately Owned Companion Dog as a Model for Alzheimers DiseaseR24AG073137 · NIA · UNIVERSITY OF WASHINGTON · PI KEENE, CHRISTOPHER DIRK, MCGRATH, STEPHANIE · 2021 to 2024
$5.1M
NIA NIH HHS R24 AG073137NIA NIH HHS U19 AG057377
6 · The paper itself

Abstract

High-quality, well-annotated, healthy tissue specimens are crucial to the success of basic and translational research, but often difficult to procure. Postmortem (PM) tissue collections provide the opportunity to collect these healthy biospecimens. PM procurement programs led by biobanks can further contribute by providing researchers with rare biospecimens collected with short postmortem intervals (PMI) in controlled environments. To support biomedical and translational research, the Cornell Veterinary Biobank (CVB), an ISO 20387 accredited core resource at the Cornell University College of Veterinary Medicine, has performed PM tissue collections from research and privately owned animals since 2013. The CVB PM collection team, consisting of a board-certified veterinary pathologist, a licensed veterinary technician collection specialist, and a data capture specialist, performs rapid tissue collections during controlled warm necropsies, with an accepted PMI of ≤2 hours and a target PMI of ≤1 hour. A retrospective analysis of PM collections between 2013 and 2020 was completed, consisting of 4077 aliquots of 1582 biospecimens from 69 donors (48 canine, 16 feline, and 5 equine). An average of 22.93 biospecimens per donor were collected (range: 1-49). The average PMI for standard collections was 43.48 ± 2.30 minutes, starting on average 20.81 ± 1.61 minutes after time of death. Thus far, the CVB has a favorable utilization rate, with 414 aliquots (10.15%) from 350 specimens (20.12%) and 45 animals (65.22%) distributed to researchers. The success of the CVB PM tissue biobanking program, collecting high-quality biospecimens with short PMIs, was due to support from veterinary pathologists, the competence of CVB personnel, and the continuous evolution of methods within a quality management system. Improvement of PM tissue collection programs in biobanks, with standardized practices for all processes and specialized personnel, can enhance the quality and increase utilization of its biospecimens and associated data.

Indexed as

Biomedical ResearchTissue and Organ ProcurementAnimalsBiological Specimen BanksCatsDogsHorsesHumansRetrospective StudiesTissue Banksbiobankingnecropsypostmortempostmortem intervalresearch autopsytissue

Identifiers

PMID35930257
PMCPMC9963475
OpenAlexW4289971481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.