ArticleArchives of microbiology2022
The effect of young blood plasma administration on gut microbiota in middle-aged rats.
Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Biochemical and structural improvements in ileum and colon with concurrent gut microbiota enhancement through intermittent fasting plasma infusions.Scientific reports · 2025Article
- Therapeutic potential of young plasma in reversing age-related liver inflammation via modulation of NLRP3 inflammasome and necroptosis.Biogerontology · 2025Article
- Rejuvenating the gut: young plasma therapy improves cell proliferation, IGF-I and IGF-IR expression, and immune defense in aged male rats jejunum.Biogerontology · 2025Article
- Plasma therapy: a novel intervention to improve age-induced decline in deudenal cell proliferation in female rat model.Biogerontology · 2025Article
- How Does Plasma Therapy Approach Affect VDR Expression in the Elderly?Journal of clinical practice and research · 2025Article
- Effect of middle-age plasma therapy on ileum morphology, immune defense (IgA) and cell proliferation (Ki-67) of female aged rats.Histochemistry and cell biology · 2024Article
- Article
- Exploring the therapeutic potential of plasma from intermittent fasting and untreated rats on aging-induced liver damage.Journal of cellular and molecular medicine · 2024Article
- Supplementing probiotics during intermittent fasting proves more effective in restoring ileum and colon tissues in aged rats.Journal of cellular and molecular medicine · 2024Article
- Reduced liver damage and fibrosis with combined SCD Probiotics and intermittent fasting in aged rat.Journal of cellular and molecular medicine · 2024Article
- Heterochronic Plasma Transfer: Experimental Design, Considerations, and Technical Challenges.Rejuvenation research · 2023Review
- The rejuvenating influence of young plasma on aged intestine.Journal of cellular and molecular medicine · 2023Article
- Age-related differences in response to plasma exchange in male rat liver tissues: insights from histopathological and machine-learning assisted spectrochemical analyses.Biogerontology · 2023Article
- Bioactive nutraceuticals oligo-lactic acid and fermented soy extract alleviate cognitive decline in mice in partFrontiers in nutrition · 2023Article
- Crosstalk between the Gut and Brain in Ischemic Stroke: Mechanistic Insights and Therapeutic Options.Mediators of inflammation · 2022Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Numerous in-depth studies continue to reveal the many benefits of gut microbiota and young blood plasma administration. Dysbiosis, which occurs in the intestinal microbiota, especially in the aging process, is associated with many metabolic and cognitive disorders. Therefore, many studies aim to reverse the dysbiosis that occurs. There are also studies showing that young blood plasma application reverses the effects of aging at the level of many tissues and organs. Today, while research continues to reveal all the benefits of young blood plasma application in terms of health, blood plasma centers are also being established. In this study, we aimed to reveal the impact of young blood plasma, administered for 1 month, on the intestinal microbiota of middle-aged rats. After detailed metagenome analysis, alpha diversity indices demonstrated greater bacterial richness in the microbiota of plasma-administered rats compared with control rats. In addition, the Firmicutes/Bacteroidetes ratio was significantly diminished in plasma group microbiota, confirming possible rejuvenation properties of young plasma. Furthermore, increased counts of Bifidobacterium longum, Coprococcus catus, and Romboutsia ilealis species were measured in plasma-administered rats. The study revealed many fluctuations in different bacterial taxonomic units of the microbiota that could be valuable in future research on blood-based anti-aging treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.