Evidence map›Paper›PMID 35929921›Full record

ArticleTurkish journal of urology2021

Current role of cytoreductive nephrectomy in metastatic renal cell carcinoma.

Charles Van Praet, Charlotte Slots, Nikhil Vasdev, Sylvie Rottey, Valérie Fonteyne, Iulia Andras, Maarten Albersen, Gert De Meerleer, Axel Bex, Karel Decaestecker

Open access · greenAbstract read
In one paragraph

Article in Turkish journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Charles Van PraetDepartment of Urology, ERN eUROGEN accredited centre, Ghent University Hospital, Ghent University, Ghent, Belgium.
Charlotte SlotsDepartment of Urology, ERN eUROGEN accredited centre, Ghent University Hospital, Ghent University, Ghent, Belgium.
Nikhil VasdevDepartment of Urology, Hertfordshire and Bedfordshire Urological Cancer Centre, Lister Hospital Stevenage, School of Medicine and Life Sciences, University of Hertfordshire, Hatfield, the UK.
Sylvie RotteyDepartment of Medical Oncology, Ghent University Hospital, Ghent, Belgium.
Valérie FonteyneDepartment of Radiation Oncology, Ghent University Hospital, Ghent, Belgium.
Iulia AndrasDepartment of Urology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Maarten AlbersenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Gert De MeerleerDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Axel BexDepartment of Urology, Royal Free Hospital NHS Foundation Trust, London, the UK.
Karel DecaesteckerDepartment of Urology, ERN eUROGEN accredited centre, Ghent University Hospital, Ghent University, Ghent, Belgium.
Ghent University Hospital · BEKU Leuven · BEIuliu Hațieganu University of Medicine and Pharmacy · RORoyal Free London NHS Foundation Trust · GBUniversity of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, immediate cytoreductive nephrectomy (CN) was considered the standard of care in patients with metastatic renal cell carcinoma (mRCC) who were fit enough to undergo surgery. Recently, 2 randomized controlled trials, SURTIME and CARMENA, have questioned the role of immediate CN and initiated an ongoing debate on the proper indications and timing of CN. Although some patients still benefit from immediate CN, other patients require immediate systemic treatment, and some of them might benefit from deferred CN in the absence of disease progression. This study provides an overview of the history of CN, an in-depth analysis of SURTIME and CARMENA, and highlights the current indications for performing immediate or deferred CN.

Identifiers

PMID35929921
PMCPMC8057358
OpenAlexW3126681775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.