Evidence map›Paper›PMID 35929609›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Membrane Manipulation of Giant Unilamellar Polymer Vesicles with a Temperature-Responsive Polymer.

Marina de Souza Melchiors, Tsvetomir Ivanov, Iain Harley, Claudia Sayer, Pedro H H Araújo, Lucas Caire da Silva, Calum T J Ferguson, Katharina Landfester

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Peptide-Induced Division of Polymersomes for Biomimetic Compartmentalization.Angewandte Chemie (International ed. in English) · 2024
    Article
  7. Shape Transformation of Polymer Vesicles.Accounts of materials research · 2024
    Article
  8. Article
  9. Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marina de Souza MelchiorsDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0001-7236-8283
Tsvetomir IvanovDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0002-0199-9472
Iain HarleyDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0002-3767-4450
Claudia SayerDepartment of Chemical Engineering and Food Engineering, Federal University of Santa Catarina, P.O. Box 476, 88040-900, Florianópolis-SC, Brazil.ORCID 0000-0003-1044-2905
Pedro H H AraújoDepartment of Chemical Engineering and Food Engineering, Federal University of Santa Catarina, P.O. Box 476, 88040-900, Florianópolis-SC, Brazil.ORCID 0000-0001-5905-0158
Lucas Caire da SilvaDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0003-4663-3471
Calum T J FergusonDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0002-6168-4624
Katharina LandfesterDepartment of Physical Chemistry of Polymers, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.ORCID 0000-0001-9591-4638

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the complex behavior and dynamics of cellular membranes is integral to gain insight into cellular division and fusion processes. Bottom-up synthetic cells are as a platform for replicating and probing cellular behavior. Giant polymer vesicles are more robust than liposomal counterparts, as well as having a broad range of chemical functionalities. However, the stability of the membrane can prohibit dynamic processes such as membrane phase separation and division. Here, we present a method for manipulating the membrane of giant polymersomes using a temperature responsive polymer. Upon elevation of temperature deformation and phase separation of the membrane was observed. Upon cooling, the membrane relaxed and became homogeneous again, with infrequent division of the synthetic cells.

Indexed as

Artificial CellsUnilamellar LiposomesPhase TransitionPolymersTemperaturePolymersUnilamellar LiposomesBiomimetic MembranesBlock CopolymersMembrane ManipulationPhase SeparationPolymersomes

Identifiers

PMID35929609
PMCPMC9804479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.