Evidence map›Paper›PMID 35929516›Full record

ArticleBiomaterials science2022

pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss.

Hunter Newman, Jiaul Hoque, Yu-Ru V Shih, Gabrielle Marushack, Unghyeon Ko, Gavin Gonzales, Shyni Varghese

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Branched poly-l-lysine for cartilage penetrating carriers.Bioengineering & translational medicine · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hunter NewmanDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27710, USA. shyni.varghese@duke.edu.
Jiaul HoqueDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC 27710, USA.
Yu-Ru V ShihDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC 27710, USA.
Gabrielle MarushackDepartment of Biomedical Engineering, Duke University, Durham, NC 27710, USA.
Unghyeon KoDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC 27710, USA.
Gavin GonzalesDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC 27710, USA.
Shyni VargheseDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27710, USA. shyni.varghese@duke.edu.ORCID http://orcid.org/0000-0002-0004-7947
Duke University · US

Funding

Modulation of local adenosine signaling to attenuate fracture painR01AR079189 · NIAMS · DUKE UNIVERSITY · PI VARGHESE, SHYNI · 2021 to 2025
$2.8M
Localization of adenosine to promote fracture healingR01AG074491 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Shyni Varghese · 2022 to 2026
$2.6M
Adenosine A2B Receptor in Bone Health and OsteoporosisR01AR071552 · NIAMS · DUKE UNIVERSITY · PI VARGHESE, SHYNI · 2017 to 2021
$2.4M
NIAMS NIH HHS R01 AR071552NIAMS NIH HHS R01 AR079189NIA NIH HHS R01 AG074491
6 · The paper itself

Abstract

Bone tissue undergoes continuous remodeling

Indexed as

Bone ResorptionOsteoporosisAdenosineAnimalsHyaluronic AcidHydrogen-Ion ConcentrationMiceOsteoclastsAdenosineHyaluronic Acid

Identifiers

PMID35929516
PMCPMC9894097
OpenAlexW4289323600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.