Evidence map›Paper›PMID 35929043›Full record

ArticleInfection control and hospital epidemiology2023

Lukas Bechmann, Ralf Böttger, Claas Baier, Aljoscha Tersteegen, Katja Bauer, Achim J Kaasch, Gernot Geginat

Open access · hybridAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. International journal of molecular sciences · 2026
    Review
  3. From Environmental Organism to Nosocomial Threat:Antibiotics (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A rare case of successful treatment of peritoneal dialysis patient withFrontiers in cellular and infection microbiology · 2024
    Review
  12. Review
  13. Frontiers in cellular and infection microbiology · 2023
    Article
  14. Molecular epidemiology of enterically colonizingFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lukas BechmannDepartment of Medical Microbiology and Infection Control, Otto-von-Guericke UniversityMagdeburg, Germany.ORCID https://orcid.org/0000-0001-8144-5033
Ralf BöttgerDepartment of Pediatrics, Otto-von-Guericke UniversityMagdeburg, Germany.
Claas BaierInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School (MHH), Germany.
Aljoscha TersteegenDepartment of Medical Microbiology and Infection Control, Otto-von-Guericke UniversityMagdeburg, Germany.ORCID https://orcid.org/0000-0003-2602-2040
Katja BauerDepartment of Medical Microbiology and Infection Control, Otto-von-Guericke UniversityMagdeburg, Germany.
Achim J KaaschDepartment of Medical Microbiology and Infection Control, Otto-von-Guericke UniversityMagdeburg, Germany.ORCID https://orcid.org/0000-0002-6659-6738
Gernot GeginatDepartment of Medical Microbiology and Infection Control, Otto-von-Guericke UniversityMagdeburg, Germany.
Otto-von-Guericke-Universität Magdeburg · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInvestigation of the origin of a

designRetrospective case-control study.

settingRegional level 3 perinatal center in Germany. PATIENTS: This study included 4

methodsA case-control study was performed to identify the source of the outbreak. The molecular investigation of S. marcescens isolates collected during the outbreak was performed using pulsed-field gel electrophoresis and next-generation sequencing.

resultsThe retrospective case-control study showed a significant correlation (P < .0001) between S. marcensens infection or colonization and consumption of donor milk that had tested negative for pathogenic bacteria from a single breast milk donor. Pulsed-field gel electrophoresis and next-generation sequencing retrospectively confirmed an S. marcescens strain isolated from the breast milk of this donor as the possible origin of the initial outbreak. The outbreak was controlled by the implementation of an infection control bundle including a multidisciplinary infection control team, temporary nutrition of infants with formula only and/or their mother's own milk, repeated screening of all inpatients, strict coat and glove care, process observation, retraining of hand hygiene and continuous monitoring of environmental cleaning procedures.

conclusionsLow-level contaminated raw donor milk can be a source of infection and colonization of preterm infants with S. marcescens even if it tests negative for bacteria.

Indexed as

Cross InfectionSerratia InfectionsCase-Control StudiesDisease OutbreaksElectrophoresis, Gel, Pulsed-FieldFemaleHumansInfantInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMilk, HumanRetrospective StudiesSerratia marcescens

Identifiers

PMID35929043
PMCPMC10262161
OpenAlexW4289943090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.