Evidence map›Paper›PMID 35928942›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Advances and trends in microbial production of polyhydroxyalkanoates and their building blocks.

Qiang Gao, Hao Yang, Chi Wang, Xin-Ying Xie, Kai-Xuan Liu, Ying Lin, Shuang-Yan Han, Mingjun Zhu, Markus Neureiter, Yina Lin and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Qiang GaoKey Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, QH, China.
Hao YangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Chi WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Xin-Ying XieSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Kai-Xuan LiuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Ying LinSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Shuang-Yan HanSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Mingjun ZhuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Markus NeureiterInstitute for Environmental Biotechnology, Department of Agrobiotechnology, University of Natural Resources and Life Sciences, Tulln, Austria.
Yina LinSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Jian-Wen YeSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
South China University of Technology · CNQinghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rapid development of synthetic biology, a variety of biopolymers can be obtained by recombinant microorganisms. Polyhydroxyalkanoates (PHA) is one of the most popular one with promising material properties, such as biodegradability and biocompatibility against the petrol-based plastics. This study reviews the recent studies focusing on the microbial synthesis of PHA, including chassis engineering, pathways engineering for various substrates utilization and PHA monomer synthesis, and PHA synthase modification. In particular, advances in metabolic engineering of dominant workhorses, for example

Indexed as

metabolic engineeringmicrobial productionPHA synthasepolyhydroxyalkanoatessynthetic pathway

Identifiers

PMID35928942
PMCPMC9343942
OpenAlexW4285794044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.