Evidence map›Paper›PMID 35928914›Full record

ArticleBioMed research international2022

Duration of Acute Kidney Injury and In-Hospital Mortality in Elder Patients with Severe COVID-19: A Retrospective Cohort Study.

Yue Cai, Chong Tang, Yun Song, Qinglin Li, Shanshan Guo, Yanyan Chen, Fang Wang, Yangping Li, Yan Lei, Fei Li and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yue CaiDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.ORCID https://orcid.org/0000-0002-3335-0192
Chong TangDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.
Yun SongDepartment of Respiratory Medicine, Xijing Hospital, Changle West Road, Xi'an 710032, China.
Qinglin LiDepartment of Critical Care Medicine, The First Medical Centre, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.
Shanshan GuoDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.
Yanyan ChenDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.
Fang WangDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.
Yangping LiHuo Shen Shan Hospital, Wuhan, China.
Yan LeiHuo Shen Shan Hospital, Wuhan, China.ORCID https://orcid.org/0000-0002-2607-2462
Fei LiDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.ORCID https://orcid.org/0000-0003-1081-7105
Ling TaoDepartment of Cardiology, Xijing Hospital, Changle West Road, Xi'an 710032, China.ORCID https://orcid.org/0000-0002-7076-1185

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with severe coronavirus disease 2019 (COVID-19) who develop acute kidney injury (AKI) in the intensive care unit (ICU) have extremely high rates of mortality. This study evaluated the prognostic impact of AKI duration on in-hospital mortality in elder patients. Methods: We performed a retrospective study of 126 patients with confirmed COVID-19 with severe or critical disease who treated in the ICU from February 4, 2020, to April 16, 2020. AKI was defined according to the Kidney Disease Improving Global Outcomes serum creatinine (Scr) criteria. AKI patients were divided into transient AKI and persistent AKI groups based on whether Scr level returned to baseline within 48 h post-AKI. Results: In total, 107 patients were included in the final analysis. The mean age was 70 (64-78) years, and 69 (64.5%) patients were men. AKI occurred in 48 (44.9%) during their ICU stay. Of these, 11 (22.9%) had transient AKI, and 37 (77.9%) had persistent AKI. In-hospital mortality was 18.6% ( Conclusions: AKI duration can be an important predictive parameter in elder patients suffering from COVID-19 and are admitted to ICU. Among these patients, those exhibiting persistent AKI have a lower in-hospital survival rate than those with transient AKI, emphasizing the importance of identifying an appropriate treatment window for early intervention.

Indexed as

Acute Kidney InjuryCOVID-19AgedFemaleHospital MortalityHumansIntensive Care UnitsMaleRetrospective StudiesRisk Factors

Identifiers

PMID35928914
PMCPMC9345708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.