Evidence map›Paper›PMID 35928899›Full record

ArticleFrontiers in endocrinology2022

Differentially Regulated Apolipoproteins and Lipid Profiles as Novel Biomarkers for Polypoidal Choroidal Vasculopathy and Neovascular Age-Related Macular Degeneration.

Xinyuan Zhang, Bingjie Qiu, Zhizhong Gong, Xiaosi Chen, Yanhong Wang, Yao Nie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xinyuan ZhangBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Bingjie QiuBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Zhizhong GongDivision of Medical Affairs, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Xiaosi ChenBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yanhong WangDepartment of Epidemiology and Biostatistics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College, Beijing, China.
Yao NieBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Tongren Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid dyshomeostasis has been implicated in the pathogenesis of various retinal and choroidal vascular diseases. This study aims to investigate whether apolipoprotein (apo) mediated differential regulation of lipid metabolism contributes to the phenotypes of polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (nAMD). This study involved 148 subjects including 53 patients with PCV, 44 patients with nAMD, and 51 age-, sex-matched subjects with normal fundus controls. Routine blood biochemistry profile was evaluated. Apolipoproteins was estimated by Luminex technology. After controlling for age, gender, body mass index, duration of hypertension and type 2 diabetes mellitus, apoB/non-high density lipoprotein cholesterol (HDL-C) (

Indexed as

Apolipoprotein B-100Apolipoproteins BChoroidal NeovascularizationMacular DegenerationApolipoproteinsBiomarkersCholesterol, LDLHumansAPOB protein, humanApolipoprotein B-100ApolipoproteinsApolipoproteins BBiomarkersCholesterol, LDLapolipoproteinsneovascular age-related macular degenerationpolypoidal choroidal vasculopathyregulatory mechanismsserum lipid profiles

Identifiers

PMID35928899
PMCPMC9343613
OpenAlexW4285798640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.