Evidence map›Paper›PMID 35928619›Full record

ArticleJournal of thoracic disease2022

Efficacy of low-dose corticosteroids in patients with acute respiratory distress syndrome: a prospective observational study.

Ruoyang Zhang, Xu Huang, Haining Lu, Guohui Fan, Ying Cai, Ye Tian, Jingen Xia, Wang Deng, Daoxin Wang, Junlu Li and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ruoyang Zhang *China-Japan Friendship Hospital, Capital Medical University, Beijing, China.
Xu Huang *Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital & National Clinical Research Center for Respiratory Diseases & Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Haining Lu *Department of Critical Care Medicine, Qilu Hospital of Shandong University (Qingdao), Qingdao, China.
Guohui FanDepartment of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital & National Clinical Research Center for Respiratory Diseases & Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Ying CaiDepartment of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital & National Clinical Research Center for Respiratory Diseases & Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Ye TianDepartment of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital & National Clinical Research Center for Respiratory Diseases & Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Jingen XiaDepartment of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital & National Clinical Research Center for Respiratory Diseases & Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Wang DengDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University Chongqing, China.
Daoxin WangDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University Chongqing, China.
Junlu LiDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shilei WangDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lihua XingDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shaohua LiuIntensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Tongwen SunIntensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Dawei WuDepartment of Critical Care Medicine, Qilu Hospital of Shandong University (Qingdao), Qingdao, China.
Qingyuan ZhanChina-Japan Friendship Hospital, Capital Medical University, Beijing, China.
Chen WangChina-Japan Friendship Hospital, Capital Medical University, Beijing, China.
CHARDSnet group*
CHARDSnet group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is still no agreement on whether corticosteroids can reduce mortality in patients with acute respiratory distress syndrome (ARDS). The aim of this study was to investigate the efficacy of low-dose corticosteroid administration in patients with ARDS. Methods: A prospective observational study of patients with ARDS in 17 hospitals in China was performed between March 2016 and February 2018. Propensity score matching was performed to adjust for differences in baseline characteristics between different groups. The effects of corticosteroids were assessed by using the Kaplan-Meier method and a multivariate Cox regression. Results: A total of 527 ARDS patients were enrolled in the study. Sixty-five patients (12.3%) were administered low-dose (methylprednisolone ≤1 mg·kg Conclusions: The administration of low-dose corticosteroids may reduce mortality in patients with ARDS.

Indexed as

Acute respiratory distress syndrome (ARDS)corticosteroidmortality

Identifiers

PMID35928619
PMCPMC9344422

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.