Evidence map›Paper›PMID 35928600›Full record

ArticlePhysics and imaging in radiation oncology2022

Technical feasibility of online adaptive stereotactic treatments in the abdomen on a robotic radiosurgery system.

Maaike T W Milder, Alba Magallon-Baro, Wilhelm den Toom, Erik de Klerck, Lorne Luthart, Joost J Nuyttens, Mischa S Hoogeman

Open access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maaike T W MilderErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Alba Magallon-BaroErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Wilhelm den ToomErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Erik de KlerckErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Lorne LuthartErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Joost J NuyttensErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Mischa S HoogemanErasmus MC, University Medical Center Rotterdam, Department of Radiotherapy, The Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Stereotactic body radiotherapy (SBRT) has been proven to be beneficial for several disease sites in the (lower) abdomen. However, the quality of the treatment plan, based on a single planning computed tomography (CT), can be compromised due to large inter-fraction motion of the target and organs at risk (OARs) in this anatomical region. The aim of this study was to investigate the feasibility of online adaptive SBRT treatments on a robotic radiosurgery system and to record estimated total treatment times. Materials and methods: For two disease sites, locally advanced pancreatic cancer (LAPC) and oligometastatic lymph nodes, four patients with repeat CTs were included in the feasibility study. Quick treatment plan templates were generated based on the planning CT and validated by running them on the plan and fraction CTs. For two cases a dummy run was performed and the individual steps were timed. Dose delivery was the largest contributor to the total treatment time, followed by contour adaptation. Results: Running the quick plan templates resulted in plans similar to unrestricted plans, obeying the OAR constraints. The dummy runs showed that online adaptive treatments were completed in 64 to 83 min respectively for oligometastases and LAPC, comparable to other clinically available solutions. Conclusions: This study showed the feasibility of online re-planning for two challenging disease sites within a clinically acceptable time frame on a robotic radiosurgery system, making use of commercially available elements that are not integrated by the vendor.

Indexed as

AdaptiveARTCyberKnifeLAPCOligometastasesSBRT

Identifiers

PMID35928600
PMCPMC9344339
OpenAlexW4288456983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.