Evidence map›Paper›PMID 35928492›Full record

ArticleFrontiers in public health2022

Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation.

Xingdong Cheng, Rongzhi Zhang, Shilin Wei, Jian Huang, Kerong Zhai, Yongnan Li, Bingren Gao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xingdong ChengDepartment of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Rongzhi ZhangDepartment of Anesthesiology, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Shilin WeiDepartment of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Jian HuangDepartment of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Kerong ZhaiDepartment of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Yongnan LiDepartment of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Bingren GaoDepartment of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Lanzhou University · CNLanzhou University Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial ischemia causes myocardial inflammation. Research indicates that the venoarterial extracorporeal membrane oxygenation (VA ECMO) provides cardiac support; however, the inflammatory response caused by myocardial ischemia remains unresolved. Dexamethasone (Dex), a broad anti-inflammatory agent, exhibits a cardioprotective effect. This study aims to investigate the effect of Dex on a rat model of acute myocardial infarction (AMI) supported by VA ECMO. Male Sprague-Dawley rats (300-350 g) were randomly divided into three groups: Sham group (

Indexed as

DexamethasoneExtracorporeal Membrane OxygenationMyocardial InfarctionMyocardial IschemiaAnimalsMaleRatsRats, Sprague-DawleyDexamethasoneacute myocardial infarctionapoptosisdexamethasoneinflammatory responsevenoarterial extracorporeal membrane oxygenation

Identifiers

PMID35928492
PMCPMC9343845
OpenAlexW4285797843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.