ArticleFrontiers in medicine2022
Higher Adherence to the Mediterranean Dietary Pattern Is Inversely Associated With Severity of COVID-19 and Related Symptoms: A Cross-Sectional Study.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Relevance of Mediterranean diet as a nutritional strategy in diminishing COVID-19 risk: A systematic review.PloS one · 2024Pooled it
- Diet Quality and Risk of SARS-CoV-2 Infection or COVID-19: A Systematic Review of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Adherence to the Mediterranean diet, particularly olive oil intake, and metabolic health parameters are independently associated with SARS-CoV-2 vaccine-induced IgG responses.Metabolism open · 2026Article
- Investigating the association between major dietary patterns and disease outcomes in diabetic and non-diabetic patients with COVID-19: a cross-sectional study.Journal of diabetes and metabolic disorders · 2025Article
- The Impact of Diet Quality on COVID-19 Severity and Outcomes-A Scoping Review.Current nutrition reports · 2025Article
- The association between nutrient patterns and hospital stay duration and symptoms in COVID-19 in Iranian patients: cross-sectional study.Frontiers in nutrition · 2025Article
- Observational
- Comparison of DASH diet score and total antioxidant capacity of diet on serum levels of TMPRSS-2, inflammatory biomarkers, and disease severity in COVID-19 patients: A case-control study.Food science & nutrition · 2024Article
- Association of major dietary patterns with socioeconomic status, obesity, and contracting COVID-19 among Iranian adults.Frontiers in nutrition · 2024Article
- The association between dietary intakes of zinc, vitamin C and COVID-19 severity and related symptoms: A cross-sectional study.Clinical nutrition ESPEN · 2023Article
- Supplementation use and diet changes during COVID-19 pandemic according to anxiety level and Mediterranean diet adherence.Clinical nutrition ESPEN · 2023Article
- Role of micronutrients in the modulation of immune system and platelet activating factor in patients with COVID-19; a narrative review.Frontiers in nutrition · 2023Review
- Association between dietary glycemic index and non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2023Article
- Association between dietary antioxidant quality score and severity of coronavirus infection: a case-control study.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Adherence to the Mediterranean diet (MD) has been associated with a decreased risk of developing a variety of chronic diseases that are comorbidities in COVID-19 patients. However, its association to the severity and symptoms of COVID-19 are still unknown. This study aimed to examine the association between adherence to the MD pattern and COVID-19 severity and symptoms in Iranian hospitalized patients. Methods: In this cross-sectional study, 250 COVID-19 patients aged 18 to 65 were examined. We employed a food frequency questionnaire (FFQ) to obtain data on dietary intake of participants in the year prior to their COVID-19 diagnosis. COVID-19 severity was determined using the National Institutes of Health's Coronavirus Disease 2019 report. Additionally, symptoms associated with COVID-19, inflammatory markers, and other variables were evaluated. The scoring method proposed by Trichopoulou et al. was used to assess adherence to the MD. Results: The participants' mean age was 44.1 ± 12.1 years, and 46% of them had severe COVID-19. Patients who adhered more closely to the MD had lower serum C-reactive protein levels (7.80 vs. 37.36 mg/l) and erythrocyte sedimentation rate (14.08 vs. 42.65 mm/h). Those with the highest MD score were 77% less likely to have severe COVID-19 after controlling for confounding variables. The MD score was also found to be inversely associated with COVID-19 symptoms, including dyspnea, cough, fever, chills, weakness, myalgia, nausea and vomiting, and sore throat. Conclusion: Higher adherence to the MD was associated with a decreased likelihood of COVID-19 severity and symptoms, as well as a shorter duration of hospitalization and convalescence, and inflammatory biomarkers.
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