Evidence map›Paper›PMID 35928286›Full record

ArticleEuropean heart journal open2021

Androgen receptor polymorphism, testosterone levels, and prognosis in patients with acute myocardial infarction.

Anne Wang, John Flanagan, Stefan Arver, Anna Norhammar, Per Näsman, Lars Rydén, Linda G Mellbin

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anne WangCardiology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm 171 76, Sweden.ORCID https://orcid.org/0000-0002-4047-7730
John FlanaganCenter for Andrology and Sexual Medicine (ANOVA), Department of Medicine, Huddinge, Karolinska Institutet, Stockholm 141 86, Sweden.
Stefan ArverCenter for Andrology and Sexual Medicine (ANOVA), Department of Medicine, Huddinge, Karolinska Institutet, Stockholm 141 86, Sweden.
Anna NorhammarCardiology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm 171 76, Sweden.
Per NäsmanCenter for Safety Research, KTH Royal Institute of Technology, SE-100 44, Sweden.
Lars RydénCardiology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm 171 76, Sweden.
Linda G MellbinCardiology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm 171 76, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SEKTH Royal Institute of Technology · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Low testosterone has been associated with cardiovascular disease in men but with contradictory findings. Testosterone bind to the androgen receptor and polymorphisms of the receptor gene such as CAG repeat length may affect transcriptional activity, possibly mitigating testosterone effects. The aims were to study the CAG repeat length and testosterone levels at four time points following a myocardial infarction (MI) and to analyse possible relationships between CAG repeat length and cardiovascular prognosis. Methods and results: Male patients admitted for acute MI ( Conclusion: CAG repeat length was not associated with testosterone levels or prognosis in men with acute MI.

Indexed as

Androgen receptorCardiovascular diseaseDiabetesGeneticsTestosterone

Identifiers

PMID35928286
PMCPMC9241568
OpenAlexW3193604303

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.