ReviewJournal of the Endocrine Society2022
Revisiting Pituitary Apoplexy.
Review in Journal of the Endocrine Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Pooled it
- Pituitary apoplexy in cushing's disease: a single center study and systematic literature review.Pituitary · 2024Pooled it
- Pooled it
- Pituitary Apoplexy Precipitated by Non-Cranial Surgeries: An Institutional Experience.Journal of neurological surgery. Part B, Skull base · 2026Article
- Nivolumab rechallenge after pituitary apoplexy associated with nivolumab plus ipilimumab in a patient with pituitary adenoma and rectal melanoma: a case report and literature review.Journal of pharmaceutical health care and sciences · 2026Article
- Article
- Trauma Unmasking Pituitary Apoplexy: Coexisting Epidural Hematoma and Sellar Mass - A Case Report with Selected Cases from the Literature.International medical case reports journal · 2026Article
- Pituitary incidentaloma: a Pituitary Society international consensus guideline statement.Nature reviews. Endocrinology · 2025Review
- [Spontaneous remission of neuroendocrine diseases due to apoplexy in hormonally active pituitary adenomas].Problemy endokrinologii · 2025Review
- Article
- Unveiling postpartum pituitary apoplexy through atypical presentation: A case report and review of literature.Radiology case reports · 2025Article
- Epidemiology, presentation and outcomes in pituitary apoplexy: a population-based study in Malta.Endocrine oncology (Bristol, England) · 2025Article
- [Cephalgic syndrome in patients with acromegaly].Problemy endokrinologii · 2024Review
- An atypical case of fatal 'esophageal apoplexy': post-mortem findings and differential diagnosis.International journal of legal medicine · 2024Article
- Exploring risk factors of severe pituitary apoplexy: Insights from a multicenter study of 71 cases.Endocrine · 2024Article
- Pituitary apoplexy: a comprehensive analysis of 93 cases across functioning and non-functioning pituitary adenomas from a single-center.Pituitary · 2024Article
- Article
- Apoplexy of a giant clival ectopic prolactinoma: A very rare case report.International journal of surgery case reports · 2024Article
- Pituitary Apoplexy: An Updated Review.Journal of clinical medicine · 2024Review
- Pituitary Apoplexy in Macroadenoma After Minor Surgery: An Unusual Case and Literature Review.Cureus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pituitary apoplexy (PA) is a rare clinical syndrome due to pituitary hemorrhage or infarction. It is characterized by the sudden onset of one or more of the following: severe headache, visual disturbance, nausea/vomiting, and or altered mental status. Most commonly, PA occurs in an underlying pituitary adenoma. The pathophysiology is not fully understood, but it is thought to involve elements of increased metabolic demand and/or compromise to the vasculature of the pituitary or pituitary tumor. Several risk factors have been described. Stabilization of the patient on presentation, replacement of hormonal deficiencies, and reversal of electrolyte abnormalities are the recommended initial steps in the management of patients with PA. Surgical decompression of the mass effect had been the recommended treatment for patients with PA; however, retrospective studies of patients with PA have demonstrated similar outcomes when a conservative approach is applied. This suggests that in highly selected clinical scenarios (mild visual deficit and improving symptoms), conservative management is possible. Further studies, however, are necessary to better stratify patients but are limited by the rarity of the condition and the acuity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.