Evidence map›Paper›PMID 35927993›Full record

ArticleOxidative medicine and cellular longevity2022

A Linarin Derivative Protects against Ischemia-Induced Neuronal Injury in Mice by Promoting Cerebral Blood Flow Recovery via KDELR-Dependent CSPG4 Activation.

Cong Xie, Shiqin Yue, Xiangzhu Li, Zongyang Li, Weiping Li, Guodong Huang, Guoxu Ma, Wenlan Liu, Yachao Wang, Yuan Zhang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Cong XieDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0002-3411-145X
Shiqin YueDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0003-3827-3234
Xiangzhu LiDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0002-8071-3718
Zongyang LiDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0003-4479-0676
Weiping LiDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0002-2352-7775
Guodong HuangDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0002-1687-6977
Guoxu MaInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.ORCID https://orcid.org/0000-0001-5231-6590
Wenlan LiuDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0002-6178-6700
Yachao WangDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0003-3709-5368
Yuan ZhangDepartment of Neurosurgery, Shenzhen University First Affiliated Hospital, Shenzhen Second People's Hospital, Graduate School of Guangzhou Medical University, Shenzhen University, Shenzhen 518035, China.ORCID https://orcid.org/0000-0001-8987-5986
Shenzhen Second People's Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNShenzhen University Health Science Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebral ischemic microvascular response and collateral circulation compensatory capacity are important for the outcome of ischemic stroke. Here, we sought to evaluate the effect of a linarin derivate 4'-benzylapigenin-7-

Indexed as

Brain IschemiaIschemic StrokeReperfusion InjuryAnimalsAntigensApoptosisCerebrovascular CirculationChondroitin Sulfate Proteoglycan 4GlycosidesInfarction, Middle Cerebral ArteryMiceProteoglycansReceptors, PeptideAntigensChondroitin Sulfate Proteoglycan 4GlycosidesKDEL receptorlinarinProteoglycansReceptors, Peptide

Identifiers

PMID35927993
PMCPMC9345725
OpenAlexW4288041877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.