ArticlePlant communications2022
Brassinosteroids promote thermotolerance through releasing BIN2-mediated phosphorylation and suppression of HsfA1 transcription factors in Arabidopsis.
Article in Plant communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Principles and mechanisms of plant acclimation to heat stress.Nature reviews. Molecular cell biology · 2026Review
- Overexpression ofInternational journal of molecular sciences · 2026Article
- Brassinosteroids as Central Regulators of Plant Growth, Stress Tolerance, and Agricultural Resilience.Plants (Basel, Switzerland) · 2026Review
- Adaptive response to long-term high temperatures during the reproductive development in Arabidopsis thaliana.Planta · 2026Article
- Intermolecular-Interaction-Driven Adaptive Remodeling: A Network Perspective on Plant Abiotic Stress Responses.Plants (Basel, Switzerland) · 2026Review
- Natural Variation of TaSG-D1-TaWRKY53 Module Regulates Heading Date in Wheat.Plant biotechnology journal · 2026Article
- Seed metabolomic profiling of contrasting mung bean (Vigna radiata) genotypes under heat stress.Scientific reports · 2026Article
- Transcriptomic analysis of reduced thermotolerance inFrontiers in plant science · 2026Article
- Genome-wide identification and expression analysis of the SHAGGY-like kinase gene family in foxtail millet (Frontiers in plant science · 2026Article
- Review
- Molecular Mechanisms of the Phytohormone-Heat Shock Protein Pathway in Regulating Plant Thermotolerance.Plants (Basel, Switzerland) · 2025Review
- Conservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plants.PLoS genetics · 2025Article
- Research Progress on Responses and Regulatory Mechanisms of Plants Under High Temperature.Current issues in molecular biology · 2025Review
- Molecular Networks Governing Plant Responses to Heat and Cold Stress.Plants (Basel, Switzerland) · 2025Review
- GmBSK1-GmGSK1-GmBES1.5 regulatory module controls heat tolerance in soybean.Journal of advanced research · 2025Article
- Molecular mechanism analysis of LdHSFB2a in lily thermotolerance.Stress biology · 2025Article
- The heat shock response in plants: new insights into modes of perception, signaling, and the contribution of hormones.Journal of experimental botany · 2025Review
- The maize GSK3-like kinase ZmSK1 negatively regulates drought tolerance by phosphorylating the transcription factor ZmCPP2.The Plant cell · 2025Article
- Morphological, Physiological, and Molecular Responses to Heat Stress in Brassicaceae.Plants (Basel, Switzerland) · 2025Review
- The MdHSC70-MdWRKY75 module mediates basal apple thermotolerance by regulating the expression of heat shock factor genes.The Plant cell · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High temperature adversely affects plant growth and development. The steroid phytohormones brassinosteroids (BRs) are recognized to play important roles in plant heat stress responses and thermotolerance, but the underlying mechanisms remain obscure. Here, we demonstrate that the glycogen synthase kinase 3 (GSK3)-like kinase BRASSINOSTEROID INSENSITIVE2 (BIN2), a negative component in the BR signaling pathway, interacts with the master heat-responsive transcription factors CLASS A1 HEAT SHOCK TRANSCRIPTION FACTORS (HsfA1s). Furthermore, BIN2 phosphorylates HsfA1d on T263 and S56 to suppress its nuclear localization and inhibit its DNA-binding ability, respectively. BR signaling promotes plant thermotolerance by releasing the BIN2 suppression of HsfA1d to facilitate its nuclear localization and DNA binding. Our study provides insights into the molecular mechanisms by which BRs promote plant thermotolerance by strongly regulating HsfA1d through BIN2 and suggests potential ways to improve crop yield under extreme high temperatures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.