Evidence map›Paper›PMID 35927901›Full record

ReviewCurrent medicinal chemistry2023

The Fractal Viewpoint of Tumors and Nanoparticles.

Athanasios Alexiou, Christos Tsagkaris, Stylianos Chatzichronis, Andreas Koulouris, Ioannis Haranas, Ioannis Gkigkitzis, Georgios Zouganelis, Nobendu Mukerjee, Swastika Maitra, Niraj Kumar Jha and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Athanasios AlexiouDepartment of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.
Christos TsagkarisDepartment of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.
Stylianos ChatzichronisDepartment of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.
Andreas KoulourisThoracic Oncology Center, Theme Cancer, Karolinska University Hospital, 17177 Stockholm, Sweden.
Ioannis HaranasDepartment of Physics and Computer Science, Wilfrid Laurier University, Waterloo, ON, N2L-3C5, Canada.
Ioannis GkigkitzisNOVA Department of Mathematics, 8333 Little River Turnpike, Annandale, VA 22003 USA.
Georgios ZouganelisHuman Sciences Research Centre, College of Life and Natural Sciences, University of Derby, East Midlands, DE22 1GB England, UK.
Nobendu MukerjeeDepartment of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.
Swastika MaitraDepartment of Microbiology, Adamas University, Kolkata, India.
Niraj Kumar JhaDepartment of Biotechnology, School of Engineering & Technology, Sharda University, Greater Noida, Uttar Pradesh, 201310, India.
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Mohammad Amjad KamalInstitutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Michail Nikolaou1st Oncology Department, "Saint Savas" Anticancer, Oncology Hospital, 11522 Athens, Greece.
Ghulam Md AshrafPre-Clinical Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

Institutional Fund Projects IFPDP-73-22
6 · The paper itself

Abstract

Even though the promising therapies against cancer are rapidly improved, the oncology patients population has seen exponential growth, placing cancer in 5th place among the ten deadliest diseases. Efficient drug delivery systems must overcome multiple barriers and maximize drug delivery to the target tumors, simultaneously limiting side effects. Since the first observation of the quantum tunneling phenomenon, many multidisciplinary studies have offered quantum-inspired solutions to optimized tumor mapping and efficient nanodrug design. The property of a wave function to propagate through a potential barrier offer the capability of obtaining 3D surface profiles using imaging of individual atoms on the surface of a material. The application of quantum tunneling on a scanning tunneling microscope offers an exact surface roughness mapping of tumors and pharmaceutical particles. Critical elements to cancer nanotherapeutics apply the fractal theory and calculate the fractal dimension for efficient tumor surface imaging at the atomic level. This review study presents the latest biological approaches to cancer management based on fractal geometry.

Indexed as

NanoparticlesNeoplasmsFractalsHumansPharmaceutical PreparationsPharmaceutical PreparationsBox-counting algorithmcancerchaos theorydrug deliveryfractal dimensionfractalityimaging datalacunaritynanoparticlespharmacokineticsquantum tunnelingscanning tunneling microscopesuccolarity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.