Evidence map›Paper›PMID 35927648›Full record

ArticleBMC infectious diseases2022

Vibrio vulnificus necrotizing fasciitis with sepsis presenting with pain in the lower legs in winter: a case report.

Weihua Di, Jing Cui, Hui Yu, Xiao Cui, Huanlan Sa, Zhong Fu, Bingjin Fu, Guofeng Guan, Rui Du, Cuijie Shao and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Frontiers in medicine · 2026
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  3. Severe lower limb infection byFrontiers in medicine · 2025
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  4. Heliyon · 2024
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  5. [Clinical characteristics of 11 patients withZhonghua shao shang yu chuang mian xiu fu za zhi · 2024
    Article
  6. Article
  7. Article
  8. Detection ofOpen life sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Weihua DiDepartment of Pain, Binzhou Medical University Hospital, Binzhou, 256603, China.
Jing CuiDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, 256603, China.
Hui YuDepartment of Pain, Binzhou Medical University Hospital, Binzhou, 256603, China.
Xiao CuiDepartment of Pain, Binzhou Medical University Hospital, Binzhou, 256603, China.
Huanlan SaDepartment of Pain, Binzhou Medical University Hospital, Binzhou, 256603, China.
Zhong FuDepartment of Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, 256603, China.
Bingjin FuDepartment of Foot and Ankle Surgery, Binzhou Medical University Hospital, Binzhou, 256603, China.
Guofeng GuanDepartment of Foot and Ankle Surgery, Binzhou Medical University Hospital, Binzhou, 256603, China.
Rui DuDepartment of Foot and Ankle Surgery, Binzhou Medical University Hospital, Binzhou, 256603, China.
Cuijie ShaoDepartment of Pain, Binzhou Medical University Hospital, Binzhou, 256603, China.
Yong GaoDepartment of Pain, Binzhou Medical University Hospital, Binzhou, 256603, China. gaoyongbz@163.com.ORCID http://orcid.org/0000-0002-7203-7377
Binzhou Medical University · CN

Funding

Binzhou Medical University BY2015KJ01Binzhou Medical University BY2015KYQD23Department of Health of Shandong Province 2019-0515
6 · The paper itself

Abstract

backgroundVibrio vulnificus infections develop rapidly and are associated with a high mortality rate. The rates of diagnosis and treatment are directly associated with mortality. CASE PRESENTATION: We describe an unusual case of a 61-year-old male patient with chronic liver disease and diabetes who presented with a chief complaint of pain in both lower legs due to V. vulnificus infection in winter. Within 12 h of arrival, typical skin lesions appeared, and the patient rapidly developed primary sepsis. Despite prompt appropriate antibiotic and surgical treatment, the patient died 16 days after admission.

conclusionOur case findings suggest that V. vulnificus infection should be suspected in patients with an unclear infection status experiencing pain of unknown origin in the lower legs, particularly in patients with liver disease or diabetes, immunocompromised status, and alcoholism.

Indexed as

Diabetes MellitusFasciitis, NecrotizingLiver DiseasesSepsisVibrio InfectionsVibrio vulnificusHumansLegMaleMiddle AgedPainLower leg painNecrotizing fasciitisSepsisVibrio vulnificusV. vulnificus infection

Identifiers

PMID35927648
PMCPMC9351237
OpenAlexW4289755262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.