Evidence map›Paper›PMID 35927485›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2022

Human milk feeding and wheeze in Black infants born preterm.

Anna Crist Benson, Zhengyi Chen, Nori Mercuri Minich, Curtis Tatsuoka, Lydia Furman, Kristie Ross, Anna Maria Hibbs

Registry-linked trialOpen access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01601847 (Wheezing in Black Preterm Infants), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01601847 phase4completednot on this map

Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy

TypeinterventionalSponsorCase Western Reserve UniversityRan2013 to 2017Enrolled300ConditionsWheezing, AllergyArmsCholecalciferol
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna Crist BensonUniversity Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA. apc34@case.edu.ORCID http://orcid.org/0000-0002-4572-3443
Zhengyi ChenCase Western Reserve University, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-2745-4454
Nori Mercuri MinichUniversity Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-5448-220X
Curtis TatsuokaCase Western Reserve University, Cleveland, OH, USA.
Lydia FurmanUniversity Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA.
Kristie RossUniversity Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA.
Anna Maria HibbsUniversity Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, USA.
Rainbow Babies & Children's Hospital · USCase Western Reserve University · US

Funding

Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation StrategyR01HL109293 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI HIBBS, ANNA MARIA · 2012 to 2016
$3.2M
Patient-Oriented Research and Mentoring Program in Prematurity-Associated Pulmonary MorbidityK24HL143291 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI HIBBS, ANNA MARIA · 2018 to 2022
$598k
NHLBI NIH HHS K24 HL143291NHLBI NIH HHS K24HL143291NHLBI NIH HHS R01 HL109293NHLBI NIH HHS R01HL109293
6 · The paper itself

Abstract

objectivesTo determine the association between human milk exposure at 3 months corrected gestational age and recurrent wheeze in preterm Black infants.

methodsThis is a secondary analysis of data from the D-Wheeze trial (ClinicalTrials.gov identifier NCT01601847). Associations between human milk feeding at 3 months corrected age and wheezing outcomes were examined by generalized linear models.

resultsExclusively human milk fed infants (n = 13) had significantly fewer wheezing episodes than formula fed infants (n = 230) (IRR (95% CI) = 0.25 (0.07, 0.89), p = 0.03). There were no hospitalizations in infants receiving exclusive human milk. Receiving any human milk was associated with decreased odds of hospitalization by 12 months corrected age (OR (95% CI) = 0.12 (0.02, 0.79), p = 0.03).

conclusionsExclusive human milk feeding at three months corrected gestational age is associated with decreased number of wheezing episodes in the first year of life in preterm Black infants.

Indexed as

Milk, HumanRespiratory SoundsBlack PeopleBreast FeedingFemaleHospitalizationHumansInfantInfant FormulaInfant, NewbornInfant, Premature

Identifiers

PMID35927485
PMCPMC9617763
OpenAlexW4289731188

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.