Evidence map›Paper›PMID 35927081›Full record

ArticleSurgery2022

Long-term bowel dysfunction and decision regret in diverticulitis: A mixed methods study.

Noah J Harrison, Molly M Ford, Erin M Wolf Horrell, Michael Feng, Fei Ye, Kevin C Zhang, Alexander T Hawkins

Open access · greenAbstract read
In one paragraph

Article in Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. The DIVIPACT cohort profile: Evaluating the impact of colonic diverticulosis on daily life.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Noah J HarrisonSchool of Medicine, Vanderbilt University, Nashville, TN. Electronic address: https://twitter.com/alexhawkinsmd.
Molly M FordVanderbilt University Medical Center, Division of General Surgery, Section of Colon & Rectal Surgery, Nashville, TN.
Erin M Wolf HorrellVanderbilt University Medical Center, Division of General Surgery, Section of Colon & Rectal Surgery, Nashville, TN.
Michael FengVanderbilt University Medical Center, Division of General Surgery, Section of Colon & Rectal Surgery, Nashville, TN.
Fei YeDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.
Kevin C ZhangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.
Alexander T HawkinsVanderbilt University Medical Center, Division of General Surgery, Section of Colon & Rectal Surgery, Nashville, TN. Electronic address: alex.hawkins@vumc.org.
Vanderbilt University Medical Center · USTwitter (United States) · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Novel Assessment of the Role of Surgery in Recurrent DiverticulitisK23DK118192 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HAWKINS, ALEXANDER THARRINGTON · 2018 to 2022
$788k
NCATS NIH HHS UL1 TR000445NIDDK NIH HHS K23 DK118192
6 · The paper itself

Abstract

backgroundThis study had aimed to describe long-term decision regret, bowel dysfunction, and the overall quality of life in patients with diverticulitis, and to determine if elective colectomy was associated with these patient-reported outcome measures.

methodsThis mixed-methods, survey-based study was administered to a national cohort of patients in the United States with diverticulitis. We measured decision regret (Brehaut Decision Regret), bowel dysfunction (Low Anterior Resection Syndrome score), and the overall quality of life (EuroQol 5 Dimension) in this population. We asked open-ended questions to elucidate factors that influenced patients' choices between elective colectomy and observation.

resultsAmong the 614 respondents, 294 (48%) chose between colectomy and observational management, 94 (15%) had surgery, and 157 (26%) had major Low Anterior Resection Syndrome. Of the 294 that chose between colectomy and observational management, 51 (17%) experienced decision regret. Colectomy was associated with an average decrease in the Brehaut Decision Regret score by 6 points but was not associated with a categorical measure of decision regret (Brehaut Score ≥50). Bowel dysfunction and overall quality of life were not significantly associated with colectomy. Disease-related factors, psychosocial factors, and interactions with physicians were commonly cited as reasons for pursuing colectomy or observational management.

conclusionPatients with self-reported diverticulitis describe high levels of decision regret and bowel dysfunction regardless of chosen management strategy. Physicians should be aware that psychosocial factors can strongly influence a patient's choice between colectomy and observational management. We advocated for future prospective studies using patient reported outcome metrics to improve outcomes in diverticulitis.

Indexed as

DiverticulitisIntestinal DiseasesRectal NeoplasmsColectomyElective Surgical ProceduresEmotionsHumansPostoperative ComplicationsProspective StudiesQuality of LifeSyndrome

Identifiers

PMID35927081
PMCPMC9569027
OpenAlexW4289340042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.