Evidence map›Paper›PMID 35927034›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

β Bursting in the Retrosplenial Cortex Is a Neurophysiological Correlate of Environmental Novelty Which Is Disrupted in a Mouse Model of Alzheimer's Disease.

Callum Walsh, Thomas Ridler, Gabriella Margetts-Smith, Maria Garcia Garrido, Jonathan Witton, Andrew D Randall, Jonathan T Brown

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Reciprocal molecular and cellular cholinergic working memory impairments in Alzheimer's disease model mice.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Environmental Enrichment Preserves Retrosplenial Parvalbumin Density and Cognitive Function in Female 5xFAD Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Callum WalshDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom cw685@exeter.ac.uk j.t.brown@exeter.ac.uk.
Thomas RidlerDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom.ORCID https://orcid.org/0000-0002-8236-9033
Gabriella Margetts-SmithDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom.
Maria Garcia GarridoDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom.
Jonathan WittonDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom.
Andrew D RandallDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom.
Jonathan T BrownDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, United Kingdom cw685@exeter.ac.uk j.t.brown@exeter.ac.uk.ORCID https://orcid.org/0000-0001-5269-7661
University of Exeter · GB

Funding

National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/S000844/1
6 · The paper itself

Abstract

The retrosplenial cortex (RSC) plays a significant role in spatial learning and memory and is functionally disrupted in the early stages of Alzheimer's disease (AD). In order to investigate neurophysiological correlates of spatial learning and memory in this region we employed

Indexed as

Alzheimer DiseaseGyrus CinguliAnimalsDisease Models, AnimalHippocampusMaleMiceNeuronsSpatial MemoryAlzheimer's diseasein vivo electrophysiologylocal field potentialmemorynoveltyretrosplenial cortex

Identifiers

PMID35927034
PMCPMC9480878
OpenAlexW4289782155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.